U.S. patents available from 1976 to present.
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Pharmaceutical methods of delivering folic acid

Patent 6190693 Issued on February 20, 2001. Estimated Expiration Date: Icon_subject April 16, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Assignee

Application

No. 292027 filed on 04/16/1999

US Classes:

424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/464Tablets, lozenges, or pills

Examiners

Primary: Azpuru, Carlos

Attorney, Agent or Firm

Foreign Patent References

  • 2131292 GB. 12/13/1982
  • 2 131 292 GB. 06/13/1984
  • WO 88/04927 WO. 12/13/1987
  • WO 98/04248 WO. 07/13/1997

International Classes

A61K 009/48
A61K 009/20

Abstract

This invention provides folic acid-containing pharmaceutical compositions comprising either an oral contraceptive or a hormone replacement composition. This invention also provides methods of administering folic acid to a subject using the instant pharmaceutical compositions. Finally, this invention provides a drug delivery system useful for administering the instant pharmaceutical compositions.

Other References

  • Butterworth, C.E., et al., JAMA (Jan. 1992) 267(4):528-533
  • Butterworth, C.E., et al., Am. J. Obstetrics and Gynecology (Aug. 1991) 166:803-809
  • Potischman, N. and Brinton, L.A., Cancer Causes and Control (Jul. 1995) 7:113-126
  • Boushey, C.J., et al., JAMA (Aug. 1995) 274:1049-1057
  • Landgren, F., et al., J. Intern. Med. (Nov. 1994) 237:381-388
  • Guttormsen, A.B., et al., J. Clin. Invest. (Nov. 1996) 98:2174-2183
  • Gould, P.L., Int'l. J. Pharmaceutics (May 1986) 33:201-217
  • Sturdee, D.W., Brit. J. of Obstetrics and Gynecology (Oct. 1997) 104:1109-1115
  • Nielsen, M., et al., J. Med. Chem. (Mar. 1988) 32:727-734
  • Rhode, B.M., et al., J. of the Am. College of Nutrition (Jun. 1983) 2:221-230
  • Butterworth, C.E., et al., Am. J. of Clinical Nutrition (Jan. 1982) 73-82
  • Whitehead, N., et al., JAMA (Dec. 1973) 226(12):1421-142
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