Systems, methods and computer program products for guiding the selection of therapeutic treatment regimens
Patent 6188988 Issued on February 13, 2001. Estimated Expiration Date: March 10, 2020. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
705/3, Patient record management705/2, Health care management (e.g., record management, ICDA billing)706/45, KNOWLEDGE PROCESSING SYSTEM706/46, Knowledge representation and reasoning technique706/47, Ruled-based reasoning system706/924Medical
Systems, methods and computer program products for guiding selection of a therapeutic treatment regimen for a known disease such as HIV infection are disclosed. The method comprises (a) providing patient information to a computing device (the computer device comprising: a first knowledge base comprising a plurality of different therapeutic treatment regimens for the disease; a second knowledge base comprising a plurality of expert rules for selecting a therapeutic treatment regimen for the disease; and a third knowledge base comprising advisory information useful for the treatment of a patient with different constituents of the different therapeutic treatment regimens; and (b) generating in the computing device a listing (preferably a ranked listing) of therapeutic treatment regimens for the patient; and (c) generating in the computing device advisory information for one or more treatment regimens in the listing based on the patient information and the expert rules.
Other References
Miller et al.; Summary Recommendations for Responsible Monitoring and Regulation of Clinical Software Systems, Annals of Internal Medicine, 127(9):842-845 (1997)
Ziporyn, Terra, "Computer-Assisted Medical Decision-Making: Interest Growing", The Journal of the American Medical Association, pp. 913-918, Aug. 27, 1982
Barnett, G. et al. "DXplain; An Evolving Diagnostic Decision-Support System", The Journal of the American Medical Association, pp. 67-74, Jul. 3, 1987
Merz, Beverly, "Artificial Intelligence Charts role in Medicine", american Medical News, vol. 33, No. 2, p. 3, Jan. 12, 1990
Silverman, Barry G., "Survey of Expert Critiquing Systems: Practical and Theoretical Frontiers", Communications of the ACM, vol. 35, No. 4, pp. 106-127, Apr. 1992
Molino et al, "CARE: A Knowledge-Based System for Assisting the Physician in Patient Management", Artificial Intelligence in Medecine, Strategies for Medical Reasoning-Patient Management, 1993
Johnson, Kevin B., "American Journal of Diseases in Children", Dialog File 442:AMA Journals, Dec. 1995
Ruffin, Marshall, "Information Technology, Part 2: Interactive Media Enhances Medicine", Physician Executive, vol. 22, Issue 8, Aug. 1996
McCormack, John, "Research Takes on a Second Life", Health Data Management, p. 25, Nov. 1996
Pazanni et al, "Application of an Expert System in the Management of HIV-Infected Patients", Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, vol. 15, No. 5, pp. 356-362
"UCSF Launches Website HIV Insite, A Comprehensive Online Gateway to AIDS Knowledge", Business Wire, Dialog File 148: Trade & Industry Database, Mar. 17, 1997
Detmer, William et al, "Using the Internet to Improve Knowledge Diffusion in Medicine", Communications of the ACM, vol. 40, Issue 8, pp. 101-108, Aug. 1997
Anderson, James G., "Clearing the Way for Physicians Use of Clinical Information Systems", Communications of the ACM, vol. 40, Issue 8, pp. 83-90, Aug. 1997
Walton, R. T. et al, "Evaluation of Computer Support for Prescribing (CAPSULE) Using Simulated Cases", British Medical Journal, London, vol. 315, Issue 7111, Internation Edition, pp. 791-795, Sep. 27, 1997
Evans et al, "A Computer-Assisted Management Program for Antibiotics and Other Antiinfective Agents", The New England Journal of Medicine, vol. 338, No. 4, pp. 232-238, Jan. 22, 199