Patent ReferencesPharmaceutical preparation for oral use Method of treating gastroesophageal reflux Process for the preparation of a viscosity-stable antacid composition Ingestible pharmaceutical compositions for treating upper gastrointestinal tract distress Gastrointestinal anti-irritant composition comprising sucralfate and methods of use Methods and compositions of diphenyl ether phosphate esters for the treatment of gastrointestinal disorders Multiple unit pharmaceutical preparation Multiple unit tableted dosage form of omeprazole Effervescent composition and its production Patent #: 5824339 InventorsAssigneeApplicationNo. 750934 filed on 02/13/1997US Classes:424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/472, Layered unitary dosage forms424/474Coated pills or tabletsExaminersPrimary: Spear, James M.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/22A61K 009/24 A61K 009/26 A61K 009/28 Foreign Application Priority Data1996-01-08 SEAbstractAn oral pharmaceutical dosage form comprising an acid susceptible proton pump inhibitor and one or more antacid agents or an alginate in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer and an optional separating layer in between the proton pump inhibitor and the enteric coating. The fixed formulation is in the form of multilayered tablets, sachets or multiple unit tableted dosage forms. The multiple unit dosage form is most preferred. The new fixed formulation is especially useful in the treatment of disorders associated with dyspepsia such as heartburn.Other References
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