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Use of ribose to prevent cramping and soreness in muscles

Patent 6159943 Issued on December 12, 2000. Estimated Expiration Date: Icon_subject September 24, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Inventors

Application

No. 405464 filed on 09/24/1999

US Classes:

514/23Carbohydrate (i.e., saccharide radical containing) DOAI

Examiners

Primary: Reamer, James H.

Attorney, Agent or Firm

Foreign Patent References

  • 0573466 EP 12/13/1993
  • 4228215 DE 03/13/1994

International Class

A61K 031/70

Abstract

Ribose administered before exercise reduces or prevents exercise-induced muscle cramping and soreness. Ribose taken both before and immediately after exercise further reduces or prevents exercise-induced muscle cramping and soreness.

Other References

  • Angello, D.A., et al., "Recovery of Myocardial Function and Thallium 201 Redistribution Using Ribose", American Journal of Cardiac Imaging, 3 (4), pp. 256-265, (Dec. 1989)
  • Batista, R., "Partial left ventriculectomy--the Batista procedure", European Journal of Cardio-Thoracic Surgery, 15 (Suppl. 1), pp. S12-S19, (Jan. 1999)
  • Bax, J.J., et al., "Accuracy of Currently Available Techniques for Prediction of Functional Recovery After Revascularization in Patients With Left Ventricular Dysfunction Due to Chronic Coronary Artery Disease: Comparison of Pooled Data", Journal of the American College of Cardiology, 30 (6), pp. 1451-1460, (Nov. 15, 1997)
  • Furnary, A.P., et al., "Multicenter Trial of Dynamic Cardiomyoplasty for Chronic Heart Failure", Journal of the American College of Cardiology, 28 (5), pp. 1175-1180, (Nov. 1, 1996)
  • Gross, M., et al., "Metabolism of D-Ribose Administered Continuously to Healthy Persons and to Patients with Myoadenylate Deaminase Deficiency", Klin Wochenschr, 67, pp. 1205-1213, (1989)
  • Jessup, M., "Optimizing Medical Management of the Patient with Severe Heart Failure Awaiting Cardiac Transplantation", Cardiology--In Review, 4(5), pp. 286-291, (Sep. 1996)
  • Sawada, S.G., et al., "Echocardiographic Detection of Coronary Artery Disease During Dobutamine Infusion", Circulation, 83 (5), pp. 1605-1614, (May 1991)
  • Tullson, P.C., et al., "IMP Metabolism in Human Skeletal Muscle After Exhaustive Exercise", The American Journal of Physiology, pp. 146-152, (1995)
  • Zollner et al, Klin Wochenschr, vol. 64, pp. 1281-1290, 1986
  • Tullson et al, American Journal of Physiology, vol. 261, pp. c342-c347, 199
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