NMR/MRI with hyperpolarized gas and high Tc SQUID
Patent 6159444 Issued on December 12, 2000. Estimated Expiration Date: 
September 10, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 10, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMagnetic resonance imaging using hyperpolarized noble gases Administrable compositions and methods for magnetic resonance imaging In vivo magnetic resonance vascular imaging using laser-polarized gas microbubbles 6071494 InventorsApplicationNo. 393406 filed on 09/10/1999US Classes:424/9.3, Magnetic imaging agent (e.g., NMR, MRI, MRS, etc.)436/173NUCLEAR MAGNETIC RESONANCE, ELECTRON SPIN RESONANCE OR OTHER SPIN EFFECTS OR MASS SPECTROMETRYExaminersPrimary: Hollinden, Gary E.Attorney, Agent or FirmInternational ClassA61B 005/055AbstractA method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature. |
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