Patent ReferencesDefibrillation method and apparatus Case-activating switch assembly for an implantable cardiac stimulation device Implantable cardioverter/defibrillator with adaptive shock coupling interval and method Defibrillation threshold reduction system Multidirectional ECG coherent optimal timing of defibrillation shocks System and method to reduce defibrillation requirements Low energy implantable atrial defibrillator using multiple electrodes and stimulation rates Methods and pharmaceutical compositions for oral delivery of molecular iodine Patent #: 5885592 InventorsAssigneeApplicationNo. 212033 filed on 12/14/1998US Classes:607/5Cardioverting/defibrillatingExaminersPrimary: Jastrzab, Jeffrey R.Assistant: Evanisko, George R. Attorney, Agent or FirmForeign Patent References
International ClassA61N 001/39AbstractA system and method for providing improved defibrillation thresholds. In one embodiment of the invention, following the detection of fibrillation, a pacing pulse train is applied to a pacing electrode placed in the low gradient region of the left ventricular freewall to capture the tissue. In one embodiment, a pacing rate of about 80-95% of the VF cycle length is applied to achieve capture. Once capture of the tissue of the critical region is achieved, a high energy shock is delivered when the captured tissue is in the process of activation. The defibrillation shock is delivered at the end of the pacing train, with a coupling interval of either about 80-95% of the pacing rate (i.e., about 64-90% of the VF cycle length), or, alternatively, about 5-20% of the pacing rate (i.e., about 4-19% of the VF cycle length). In an alternative embodiment of the invention, a sensing electrode array is placed in the low gradient region of the left ventricular freewall to monitor such time as a substantial percentage of the tissue of the low gradient region is in the process of activation, i.e., on the downstroke of the respective EGMs, and then delivering the defibrillation shock at that instant.Other References
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