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US Patent 6153210 - Use of locally delivered metal ions for treatment of periodontal disease

US Patent Issued on November 28, 2000
Estimated Patent Expiration Date: Icon_subject August 14, 2017Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

Periodontal disease can be treated by the administration of metal ions, preferably silver ions, to the site where the microorganisms that cause this disease reside. Administration can be to periodontal pockets or adjacent to exposed tooth roots or alveolar bone during periodontal surgical procedures. The metal ions can be administered in polymeric microparticles, deformable films or microparticles embedded within deformable films. The metal ions are particularly microbiocidal to the bacterial pathogens that are the causative agents of periodontal disease.

Other References

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Inventors

Assignee

Application

No. 911413 filed on 08/14/1997

US Classes:

424/411, Impregnated or coated nominal articles (e.g., flea collars, etc.)424/422, Implant or insert424/424, Membrane or diffusion barrier424/425, Diffusion barrier is matrix424/426, Errodable, resorbable, or dissolving424/435, Mouth424/444, Resorbable by the body424/445Dressings

Field of Search

424/411, Impregnated or coated nominal articles (e.g., flea collars, etc.)424/422, Implant or insert424/424, Membrane or diffusion barrier424/425, Diffusion barrier is matrix424/426, Errodable, resorbable, or dissolving424/435, Mouth424/444, Resorbable by the body424/445Dressings

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

US Patent References

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Inventor: Goodson
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Inventor: Jones
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Inventor: Jernberg
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5534288, Infection-resistant surgical devices and methods of making them
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5620700, Injectable drug delivery system and method
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5622498, Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof
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Inventor: Brizzolara, et al.
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5955097Pharmaceutical preparation applicable to mucosal surfaces and body tissues
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Inventor: Tapolsky, et al.

Foreign Patent References

  • 282292 CZ. 06/20/1997
  • 0 241 179 EP. 03/20/1987
  • 0508524A1 EP. 03/20/1992
  • 6154030 JP. 06/20/1994
  • 7068109B JP. 06/20/1995
  • 2078559 RU. 05/20/1997
  • 93/24103 WO. 12/20/1993
  • WO 95/29664 WO. 11/20/1995
  • WO 96/09808 WO. 04/20/1996
  • WO 97/16212 WO. 05/20/1997

International Classes

A61K 033/38
A61K 009/70
A61K 031/765
A61L 015/03

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