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US Patent 6136814 - Aqueous acyclovir product
US Patent Issued on October 24, 2000
Estimated Patent Expiration Date:
December 8, 2017Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
December 8, 2017Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractThe present invention provides a pharmaceutical product comprising an aqueous solution of acyclovir sodium contained within a sealed container constructed of an alkali resistant polymer having a CO2 permeation constant of not more than about 1×10-8 cc/cm2 /mm/sec/cmHg.The present invention further provides a ready-to-use aqueous acyclovir product for parenteral administration with improved shelf life. The present invention further provides a method of storing aqueous acyclovir sodium, a method of maintaining the pH of aqueous acyclovir sodium, a method of preventing the precipitation of acyclovir from aqueous acyclovir sodium, and a method of preventing the influx of CO2 in an aqueous acyclovir solution, which methods comprise storing aqueous acyclovir sodium according to the present invention.Other References
| InventorsAssigneeApplicationNo. 986424 filed on 12/08/1997US Classes:514/263.38, Chalcogen attached indirectly to the 9- position of the purine ring system by acyclic nonionic bonding206/530, Single unit container428/35.7, Polymer or resin containing (i.e., natural or synthetic)428/36.8Natural or synthetic rubber or rubber-like compound containingField of Search428/35.7, Polymer or resin containing (i.e., natural or synthetic)428/36.8Natural or synthetic rubber or rubber-like compound containingExaminersPrimary: Travers, RussellAttorney, Agent or FirmUS Patent References4671331, Cover for medicinal vialIssued on: 06/09/1987 Inventor: Pruden4724232, Treatment of human viral infections Issued on: 02/09/1988 Inventor: Rideout , et al.4879286, Cyclophosphamide Issued on: 11/07/1989 Inventor: Alam, et al.4879308, Aqueous nitroglycerin injection and manufacturing process Issued on: 11/07/1989 Inventor: Alam, et al.4915956, Liquid cisplatin formulations Issued on: 04/10/1990 Inventor: Alam, et al.5084480Pentamidine salts useful in the treatment of pneumocystis carinii pneumonia Issued on: 01/28/1992 Inventor: Pai, et al. Foreign Patent References
International ClassesA01N 043/90B29D 022/00 |
