Method for the recombinant production of 1,3-propanediol
Patent 6136576 Issued on October 24, 2000. Estimated Expiration Date: 
November 13, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 13, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProduction of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism Patent #: 5686276 InventorsAssigneeApplicationNo. 969683 filed on 11/13/1997US Classes:435/158, Polyhydric435/232, Lyase (4. )530/350, PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES536/23.1, DNA or RNA fragments or modified forms thereof (e.g., genes, etc.)536/23.2, Encodes an enzyme536/23.7Encodes a microbial polypeptideExaminersPrimary: Nashed, Nashaat T.Foreign Patent References
International ClassC12P 007/18AbstractThe present invention provides an improved method for the production of 1,3-propanediol from a variety of carbon sources in an organism capable of 1,3-propanediol production and comprising DNA encoding protein X of a microorganismal dehydratase or protein X in combination with at least one of protein 1, protein 2 and protein 3, which proteins are comparable to those encoded by orfY, orfX and orfW, respectively from a microorganismal dha regulon. The protein X may be isolated from a diol dehydratase or a glycerol dehydratase. The present invention also provides host cells comprising protein X that are capable of increased production of 1,3-propanediol.Other References
Field of SearchPolyhydricENZYME (E.G., LIGASES (6. ), ETC.), PROENZYME; COMPOSITIONS THEREOF; PROCESS FOR PREPARING, ACTIVATING, INHIBITING, SEPARATING, OR PURIFYING ENZYMES Oxidoreductase (1. ) (e.g., luciferase) Lyase (4. ) VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.) Chlorella Escherichia (e.g., E. coli, etc.) Encodes an enzyme DNA or RNA fragments or modified forms thereof (e.g., genes, etc.) Encodes a microbial polypeptide PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES |
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