Patent 6132762 Issued on October 17, 2000. Estimated Expiration Date: May 5, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
424/449, Transdermal or percutaneous424/401, Cosmetic, antiperspirant, dentifrice424/402, Wearing apparel, fabric, or cloth424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/447, Bandages with incorporated medicaments514/825, ARTHRITIS514/886INFLAMMATION, SKIN
A transcutaneous therapeutic formulation comprising marijuana and a carrier for the treatment of pain, inflammation, arthritis and related disorders in humans and animals.
Other References
Touitou et al., Transdermal Delivery of Tetrahydrocannabinol, Int. J. Pharm., 42/1-2 pp. 9-15, 1988
Formukong et al., Analgesic and Antiinflammatory Activityof Constituents of Cannabis-Saitiva L., Inflammation 12(4) pp. 361-372, 1988
Zurier, Robert B., "Pre-Clinical Studies Show CT-3 reduces Chronic and Acute Inflammation and Reduces Destruction of Joints", Arthritis & Rheumatism, (Jan. 1998)
Jochimsen, PR, RL Lawton, K. VerSteeg and R. Noyes, "Effect of benzppyranoperidine, a DELTA-9THC congener, on pain", Clinical Pharmacolog & Therapeutics, vol. 24 (Aug.): pp. 223-227, 1978
"Developing the Next Generation of Analgesic and Anti-inflammatory Drugs, CT-3", Atlantic Pharmaceuticals, Inc. (www.atlan.com)(1998)
Clark, WC, MN Janal, P. Zeidenberg and G Hahas, "Effects of moderate and high doses of marihuana on thermal pain: sensory decision theory analysis", Journal of Clinical Pharmacology, vol. 21 (Aug.-Sep. suppl): pp. 299S-310S (1981)
Weiss, JL, AM Watanabe, L. Lemberger, NR Tamarkin and PV Cardon, "Cardiovascular effects of delta-9 tetrahydrocannabinol in man", Journal of Clinical Pharmacology, vol. 13 (Sep.-Oct.): pp. 671-684 (1972)
Goodwin, DW, SY Hill, B. Powell and R. Schwin, "Marihuana: CNS supressant of excitant?", American Journal of Psychiatry, vol. 131 (Mar.): pp. 313-315 (1974)
Gill, EW, WDM Paton and RG Pertwee, "Preliminary experiments on the chemistry and pharmacology of cannabis", Nature, vol. 228 (Oct. 10): pp. 134-136 (1970)
Dow, GJ, FH Myers, W. Stanton and ML Devine, "Serious reacction s to oral DELTA-9 tetrahydrocannabinol in cancer chemotherapy patients", Clinical Pharmacology, vol. 3 (Jan.-Feb.): p. 14 (1984)
Zurier, RB, RG Rossetti, JH Lane, JM Goldber, SA Hunter and SH Burstein, "Dimethylheptyl-THC oic acid: a nonpsychoactive antiinflammatory agent with a cannabinoid template structure", Arthritis & Rheumatism, vol. 41 (Jan.): pp. 163-170 (1998)
Choy, EH, and DL Scott, "Drug treatment of rheumatic diseases in the 1990s:achievements and future developments", Drugs, vol. 53 (Mar.): pp. 337-348 (1997)
Schwartzfarb, L., M. Needle and M. Chavez-Chase, "Dose-related inhibition of leukocyte migration by marihuana and delta 9-tetrahydroncannabinol (THC) in vitro", Journal of Clinical Pharmacology, vol. 14 (Jan.): pp. 35-40 (1974)
The Merck Index, An Encyclopedia of Chemical, Drugs and Biologicals, Twelfth Edition, "9349 Tetrahydrocannabinols", Whitehouse Station, New Jersey (1996