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US Patent 6132762 - Transcutaneous application of marijuana

US Patent Issued on October 17, 2000
Estimated Patent Expiration Date: Icon_subject May 5, 2018Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

A transcutaneous therapeutic formulation comprising marijuana and a carrier for the treatment of pain, inflammation, arthritis and related disorders in humans and animals.

Other References

  • Touitou et al., Transdermal Delivery of Tetrahydrocannabinol, Int. J. Pharm., 42/1-2 pp. 9-15, 1988
  • Formukong et al., Analgesic and Antiinflammatory Activityof Constituents of Cannabis-Saitiva L., Inflammation 12(4) pp. 361-372, 1988
  • Zurier, Robert B., "Pre-Clinical Studies Show CT-3 reduces Chronic and Acute Inflammation and Reduces Destruction of Joints", Arthritis & Rheumatism, (Jan. 1998)
  • Jochimsen, PR, RL Lawton, K. VerSteeg and R. Noyes, "Effect of benzppyranoperidine, a DELTA-9THC congener, on pain", Clinical Pharmacolog & Therapeutics, vol. 24 (Aug.): pp. 223-227, 1978
  • "Developing the Next Generation of Analgesic and Anti-inflammatory Drugs, CT-3", Atlantic Pharmaceuticals, Inc. (www.atlan.com)(1998)
  • Clark, WC, MN Janal, P. Zeidenberg and G Hahas, "Effects of moderate and high doses of marihuana on thermal pain: sensory decision theory analysis", Journal of Clinical Pharmacology, vol. 21 (Aug.-Sep. suppl): pp. 299S-310S (1981)
  • Weiss, JL, AM Watanabe, L. Lemberger, NR Tamarkin and PV Cardon, "Cardiovascular effects of delta-9 tetrahydrocannabinol in man", Journal of Clinical Pharmacology, vol. 13 (Sep.-Oct.): pp. 671-684 (1972)
  • Goodwin, DW, SY Hill, B. Powell and R. Schwin, "Marihuana: CNS supressant of excitant?", American Journal of Psychiatry, vol. 131 (Mar.): pp. 313-315 (1974)
  • Gill, EW, WDM Paton and RG Pertwee, "Preliminary experiments on the chemistry and pharmacology of cannabis", Nature, vol. 228 (Oct. 10): pp. 134-136 (1970)
  • Dow, GJ, FH Myers, W. Stanton and ML Devine, "Serious reacction s to oral DELTA-9 tetrahydrocannabinol in cancer chemotherapy patients", Clinical Pharmacology, vol. 3 (Jan.-Feb.): p. 14 (1984)
  • Zurier, RB, RG Rossetti, JH Lane, JM Goldber, SA Hunter and SH Burstein, "Dimethylheptyl-THC oic acid: a nonpsychoactive antiinflammatory agent with a cannabinoid template structure", Arthritis & Rheumatism, vol. 41 (Jan.): pp. 163-170 (1998)
  • Choy, EH, and DL Scott, "Drug treatment of rheumatic diseases in the 1990s:achievements and future developments", Drugs, vol. 53 (Mar.): pp. 337-348 (1997)
  • Schwartzfarb, L., M. Needle and M. Chavez-Chase, "Dose-related inhibition of leukocyte migration by marihuana and delta 9-tetrahydroncannabinol (THC) in vitro", Journal of Clinical Pharmacology, vol. 14 (Jan.): pp. 35-40 (1974)
  • The Merck Index, An Encyclopedia of Chemical, Drugs and Biologicals, Twelfth Edition, "9349 Tetrahydrocannabinols", Whitehouse Station, New Jersey (1996

Inventor

Application

No. 073111 filed on 05/05/1998

US Classes:

424/449, Transdermal or percutaneous424/401, Cosmetic, antiperspirant, dentifrice424/402, Wearing apparel, fabric, or cloth424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/447, Bandages with incorporated medicaments514/825, ARTHRITIS514/886INFLAMMATION, SKIN

Field of Search

424/78.05, Anti-inflammatory or anti-irritant (e.g., anti-arthritic, etc.)424/401, Cosmetic, antiperspirant, dentifrice424/402, Wearing apparel, fabric, or cloth424/447, Bandages with incorporated medicaments424/449, Transdermal or percutaneous424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments514/825, ARTHRITIS514/886INFLAMMATION, SKIN

Examiners

Primary: Page, Thurman K.
Assistant: Seidleck, Brian K.

Attorney, Agent or Firm

US Patent References

4189491, Tetrahydrocannabinol in a method of treating glaucoma
Issued on: 02/19/1980
Inventor: Shapiro ,   et al.4343798, Topical antimicrobial anti-inflammatory compositions
Issued on: 08/10/1982
Inventor: Fawzi4369190, Analgesic composition and use thereof to ameliorate intractable pain
Issued on: 01/18/1983
Inventor: Schulte4476140, Composition and method for treatment of glaucoma
Issued on: 10/09/1984
Inventor: Sears ,   et al.4597961, Transcutaneous application of nicotine
Issued on: 07/01/1986
Inventor: Etscorn4847290, Delta 1-thc-7-oic acid and analgesic and anti-inflammatory agents
Issued on: 07/11/1989
Inventor: Burstein4876276, (3S-4S)-7-hydroxy-Ɗ6 -tetrahydrocannabinols
Issued on: 10/24/1989
Inventor: Mechoulam, et al.4933363, Method for effecting systemic delivery of delta-9-tetrahydrocannabinol
Issued on: 06/12/1990
Inventor: ElSohly5068234, 3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles
Issued on: 11/26/1991
Inventor: D'Ambra, et al.5338753, (3R,4R)-Ɗ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics
Issued on: 08/16/1994
Inventor: Burstein, et al.5389375, Stable suppository formulations effecting bioavailability of Ɗ9 -thc
Issued on: 02/14/1995
Inventor: ElSohly5508037, Stable suppository formulations effecting bioavailability of Ɗ9 -THC
Issued on: 04/16/1996
Inventor: ElSohly5607933, 3-arylcarbonyl-1(C-attached-N-heteryl)-1H-indoles
Issued on: 03/04/1997
Inventor: D'Ambra, et al.5635530, (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them
Issued on: 06/03/1997
Inventor: Mechoulam, et al.5639460, Aqueous plant extract having antiviral activity
Issued on: 06/17/1997
Inventor: Raymond5716638Composition for applying active substances to or through the skin
Issued on: 02/10/1998
Inventor: Touitou

Foreign Patent References

  • 2 274 588 GB. 08/09/1994

International Class

A61K 009/70

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