Compounds and therapies for the prevention of vascular and non-vascular pathologies
Patent 6117911 Issued on September 12, 2000. Estimated Expiration Date: April 9, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
514/648, Two aryl rings or aryl ring systems bonded directly to the same acyclic carbon564/317Oxygen or sulfur is bonded directly to the carbon and is part of the chain
The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.
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