U.S. patents available from 1976 to present.
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Compounds and therapies for the prevention of vascular and non-vascular pathologies

Patent 6117911 Issued on September 12, 2000. Estimated Expiration Date: Icon_subject April 9, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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More ...

Inventors

Assignee

Application

No. 057323 filed on 04/09/1998

US Classes:

514/648, Two aryl rings or aryl ring systems bonded directly to the same acyclic carbon564/317Oxygen or sulfur is bonded directly to the carbon and is part of the chain

Examiners

Primary: Lambkin, Deborah C.

Attorney, Agent or Firm

Foreign Patent References

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International Classes

A61K 031/135
C07C 213/00

Abstract

The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.

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