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Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent

Patent 6117855 Issued on September 12, 2000. Estimated Expiration Date: Icon_subject December 19, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Spiroketal derivatives, compositions containing them and their use as therapeutic agents Patent #: 5728695
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Inventors

Assignee

Application

No. 994063 filed on 12/19/1997

US Classes:

514/90, Chalcogen in the six-membered hetero ring514/236.2, Three or more ring hetero atoms in the additional hetero ring514/278, Spiro ring system514/329Nitrogen attached directly to the piperidine ring by nonionic bonding

Examiners

Primary: Jarvis, William R. A.

Attorney, Agent or Firm

Foreign Patent References

  • 0 577 394 EP. 01/13/1994
  • WO 95/08549 WO. 03/13/1995
  • WO 95/18124 WO. 07/13/1995
  • WO 96/05181 WO. 02/13/1996
  • WO 96/18643 WO. 06/13/1996
  • WO 96/19233 WO. 06/13/1996
  • WO 96/24353 WO. 08/13/1996

International Classes

A61K 031/675
A61K 031/535
A61K 031/44
A61K 031/445

Foreign Application Priority Data

1996-10-07 GB

Abstract

The present invention relates to the treatment or prevention of depression and/or anxiety by the administration of a combination of CNS-penetrant NK-1 receptor antagonists and an antidepressant or anti-anxiety agent.

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