U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Bioavailable chelates of creatine and essential metals

Patent 6114379 Issued on September 5, 2000. Estimated Expiration Date: Icon_subject July 7, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Inventors

Assignee

Application

No. 348359 filed on 07/07/1999

US Classes:

514/492, Heavy metal containing DOAI514/499, Copper514/501, Nickel or cobalt514/502, Iron514/505, Cadmium or chromium556/50, Nitrogen containing556/63, Nitrogen or halogen containing556/116, Nitrogen containing556/134, Nitrogen containing (e.g., zinc ethionates, etc.)556/148, Nitrogen containing (e.g., ferric chelates of ethylenediaminetetracetic acid, etc.)562/899Selenium or tellurium containing

Examiners

Primary: Nazario-Gonzalez, Porfirio

Attorney, Agent or Firm

International Classes

A61K 031/28
C07F 013/00
C07F 011/00
C07F 015/00
C07F 001/00

Abstract

A chelate comprised of creatine bonded to an essential mineral selected from the group consisting of Mg, Ca, Cu, Zn, Fe, Cr, Co, Mo, Se and Mn to form a heterocyclic ring. Preferably, the metal is Mg, but Ca, Zn, Fe, Cr and Mn are also preferred. The creatine chelates of the present invention are capable of being absorbed in the stomach or intestines via active transport without substantial metabolism of the chelate. In other words, the creatine ligand is protected by the metal from undergoing cyclization in the acidic environment of the stomach and the metal is made more bioavailable due to the presence of the creatine ligand.

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