U.S. patents available from 1976 to present.
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Guanine derivative

Patent 6107302 Issued on August 22, 2000. Estimated Expiration Date: Icon_subject September 22, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Application

No. 875173 filed on 09/22/1997

US Classes:

514/263.38, Chalcogen attached indirectly to the 9- position of the purine ring system by acyclic nonionic bonding544/229, Boron or silicon containing544/244, Polycyclo ring system having the diazine ring as one of the cyclos544/267, At 2- and 6-positions (e.g., theophyllines, etc.)544/276, Nitrogen attached directly or indirectly to the purine ring system by nonionic bonding544/277Nitrogen attached directly or indirectly to the purine ring system by nonionic bonding

Examiners

Primary: Travers, Russell

Attorney, Agent or Firm

Foreign Patent References

  • 0 308 065 EP. 03/13/1989
  • 0 596 542 EP. 05/13/1994
  • 94 29311 WO. 12/13/1994

International Classes

A01N 043/90
C07F 005/02
C07F 009/02
C07D 473/00

Foreign Application Priority Data

1995-01-20 GB

Abstract

The invention relates to an anhydrous crystalline form of (2-[2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy]ethyl L-valinate hydrochloride (otherwise known as valaciclovir hydrochloride) and a process for preparing it.

Other References

  • Antiviral Chemistry & Chemotherapy, vol. 3, No. 3. 1992, pp. 157-164 XP002000503 Beauchamp et al p. 162 left hand column
  • Antiviral Chemistry & Chemotherapy (1992) 3(3), 157-164 Beauchamp et al "Amino acid ester prodrugs of acyclovir
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