U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Growth medium for primary pancreatic tumor cell culture

Patent 6087174 Issued on July 11, 2000. Estimated Expiration Date: Icon_subject March 18, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Process for assaying cellular immunity
Patent #: 4595653
Issued on: 06/17/1986
Inventor: Kronenberg

Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
Patent #: 5342774
Issued on: 08/30/1994
Inventor: Boon, et al.

Gene therapy Patent #: 5399346
Issued on: 03/21/1995
Inventor: Anderson, et al.

Inventors

Application

No. 040703 filed on 03/18/1998

US Classes:

435/405, Contains a growth factor or growth regulator435/384, Culture medium contains a growth factor or growth regulator435/387, Medium contains a polypeptide hormone435/391, Culture medium contains an animal extract435/392, Serum435/404, Culture medium, per se435/406, Contains a polypeptide hormone435/408Contains an animal extract

Examiners

Primary: Reeves, Julie E.

Attorney, Agent or Firm

Foreign Patent References

  • 0 367 605 A2 EP. 05/18/1990
  • 0599077 EP. 10/18/1992
  • 0538952 EP. 04/18/1993
  • 53-3509 JP. 01/18/1978
  • 89/05631 WO. 06/18/1989
  • WO 90/11085 WO. 10/18/1990
  • WO 92/05262 WO. 04/18/1992
  • 92/20374 WO. 11/18/1992
  • 94/04196 WO. 03/18/1994
  • WO 94/04196 WO. 03/18/1994
  • 94/17192 WO. 08/18/1994
  • 94/27635 WO. 12/18/1994
  • WO 95/31107 WO. 11/18/1995

International Classes

C12N 005/06
C12N 005/08

Abstract

The present invention provides a method of treating cancer comprising (a) obtaining a tumor cell line, (b) modifying the tumor cell line to render it capable of producing an increased level of a cytokine relative to the unmodified tumor cell line, and (c) administering the tumor cell line to a mammalian host having at least one tumor that is the same type of tumor as that from which the tumor cell line was obtained, wherein the tumor cell line is allogeneic and is not MHC-matched to the host. The present invention also provides a pancreatic tumor cell line, a method and medium for obtaining such a tumor cell line, and a composition comprised of cells of a purified pancreatic tumor cell line.

Other References

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