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Pharmaceutical composition containing the ace inhibitor ramipril and a dihydropyridine compound

Patent 6086919 Issued on July 11, 2000. Estimated Expiration Date: Icon_subject September 12, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3644627

Combination of dihydropyridines with angiotensin converting enzymes-inhibitors
Patent #: 4703038
Issued on: 10/27/1987
Inventor: Garthoff ,   et al.

Stabilized compositions
Patent #: 4743450
Issued on: 05/10/1988
Inventor: Harris ,   et al.

Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation
Patent #: 4857520
Issued on: 08/15/1989
Inventor: Urbach ,   et al.

Stabilized medicinal substances, a process for the preparation thereof, and stable medicinal formulations
Patent #: 5151433
Issued on: 09/29/1992
Inventor: Fulbreth, et al.

Verapmil therapy
Patent #: 5160744
Issued on: 11/03/1992
Inventor: Jao, et al.

Dosage form for delivering drug in short-time period
Patent #: 5178867
Issued on: 01/12/1993
Inventor: Guittard, et al.

5236933

Inventors

Assignee

Application

No. 522267 filed on 09/12/1995

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/468, Sustained or differential release type424/472, Layered unitary dosage forms424/473With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

Foreign Patent References

  • 2070085 CA. 12/13/1992
  • 0007293 EP. 06/13/1982
  • 0158927 EP. 10/13/1985
  • 0265685 EP. 09/13/1987
  • 0288732 EP. 11/13/1988
  • 0317878 EP. 11/13/1988
  • 0508511 EP. 10/13/1992
  • 1358951 GB. 07/13/1974
  • 2164336 GB. 03/13/1986
  • WO9628185 WO. 09/13/1996

International Class

A61R 009/14

Foreign Application Priority Data

1994-09-02 SE

Abstract

The invention is directed to a pharmaceutical composition which is a combination of the ACE inhibitor ramipril and a calcium antagonist of one of the dihydropyridine type compounds felodipine, nitrendipine, nifedipine and lacidipine. The pharmaceutical composition is for use in the therapy and treatment of hypertension.

Other References

  • Br. J. Clin. Pharmac., vol. 36, (1993), pp. 323-33
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