Microfluidic method for nucleic acid purification and processing
Patent 6074827 Issued on June 13, 2000. Estimated Expiration Date: 
February 5, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 5, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSilicon semiconductor wafer for analyzing micronic biological samples Electrophoretic separating device and electrophoretic separating method Mesoscale sample preparation device and systems for determination and processing of analytes Patent #: 5726026 Inventors
ApplicationNo. 018918 filed on 02/05/1998US Classes:435/6, Involving nucleic acid435/7.93, Competitive assay435/91.2, Acellular exponential or geometric amplification (e.g., PCR, etc.)536/25.32, Labels or markers utilized (e.g., radiotracer, affinity, fluoroescent, phosphorescent, markers, etc.)536/25.4Separation or purification of polynucleotides or oligonucleotidesExaminersPrimary: Marschel, Ardin H.Assistant: Tung, Joyce Attorney, Agent or FirmInternational ClassesC12Q 001/68C12P 019/34 C07H 021/00 AbstractIntegrated microfluidic devices comprising at least an enrichment channel and a main electrophoretic flowpath are provided. In the subject integrated devices, the enrichment channel and the main electrophoretic flowpath are positioned so that waste fluid flows away from said main electrophoretic flowpath through a discharge outlet. The subject devices find use in a variety of electrophoretic applications, including clinical assays, high throughput screening for genomics and pharmaceutical applications, point-or-care in vitro diagnostics, molecular genetic analysis and nucleic acid diagnostics, cell separations, and bioresearch generally. |
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