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US Patent 6070575 - Aerosol-forming porous membrane with certain pore structure
US Patent Issued on June 6, 2000
Estimated Patent Expiration Date:
November 16, 2018Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
November 16, 2018Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA nozzle comprised of a thin, flexible membrane material having a plurality of pores is disclosed. In one embodiment, the pores have an unflexed exit aperture diameter in the range of about 0.5 to about 2 microns (preferably about 1 micron) and are positioned substantially uniformly in the material, preferably about 50 microns apart. The nozzle preferably has a conical or trumpet-shaped cross-section. In another aspect of the invention, the exit aperture of the nozzle is surrounded by an elevated area protruding above the substantially planar exit side of the membrane in order to prevent intrusion of liquid back into the nozzle. The nozzle can be used to form an aerosol containing a pharmaceutical composition from the exit side of the nozzle upon forcible application of the composition to the entrance side of the nozzle. This aerosol can be used to administer the pharmaceutical composition, for example, to the eye or to a selected portion of the respiratory tract. The nozzle is preferably a component of a container which holds a formulation of drug. | InventorsAssigneeApplicationNo. 192833 filed on 11/16/1998US Classes:128/203.12, Means for mixing treating agent with respiratory gas128/203.21Means broken or pierced to supply treating agentField of Search128/203.12, Means for mixing treating agent with respiratory gas128/203.15, Particulate treating agent carried by breathed gas128/203.23, Pocket-type draw tube having discharge aperture for air/treating agent mixture at end thereof128/203.21, Means broken or pierced to supply treating agent128/200.14, LIQUID MEDICAMENT ATOMIZER OR SPRAYER128/204.23, Means for sensing condition of user's body222/95, With wall-collapsing means239/145, POROUS OR EXTERNAL WICK DISCHARGE MEANS604/58, Powder dispenser604/62Solid units successively fed to conduit from supply means (e.g., magazine, etc.)ExaminersPrimary: Lewis, Aaron J.Assistant: Mitchell, Teena Attorney, Agent or FirmUS Patent References3934585, Method and apparatus for application of eye dropsIssued on: 01/27/1976 Inventor: Maurice4508749, Patterning of polyimide films with ultraviolet light Issued on: 04/02/1985 Inventor: Brannon , et al.4677975, Method of dispensing and/or a dispenser Issued on: 07/07/1987 Inventor: Edgar , et al.5497763, Disposable package for intrapulmonary delivery of aerosolized formulations Issued on: 03/12/1996 Inventor: Lloyd, et al.5497944, Atomising devices and methods Issued on: 03/12/1996 Inventor: Weston, et al.5533505, Disposable inhaler Issued on: 07/09/1996 Inventor: Kallstrand, et al.5544646, Systems for the intrapulmonary delivery of aerosolized aqueous formulations Issued on: 08/13/1996 Inventor: Lloyd, et al.5660166, Systems for the intrapulmonary delivery of aerosolized aqueous formulations Issued on: 08/26/1997 Inventor: Lloyd, et al.5718222, Disposable package for use in aerosolized delivery of drugs Issued on: 02/17/1998 Inventor: Lloyd, et al.5823178, Disposable package for use in aerosolized delivery of drugs Issued on: 10/20/1998 Inventor: Lloyd, et al.5829435Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles Issued on: 11/03/1998 Inventor: Rubsamen, et al. Foreign Patent References
International ClassA61M 015/00 |
