U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Aerosol-forming porous membrane with certain pore structure

Patent 6070575 Issued on June 6, 2000. Estimated Expiration Date: Icon_subject November 16, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Inventors

Assignee

Application

No. 192833 filed on 11/16/1998

US Classes:

128/203.12, Means for mixing treating agent with respiratory gas128/203.21Means broken or pierced to supply treating agent

Examiners

Primary: Lewis, Aaron J.
Assistant: Mitchell, Teena

Attorney, Agent or Firm

Foreign Patent References

  • WO 96/06581 WO. 03/11/1996

International Class

A61M 015/00

Abstract

A nozzle comprised of a thin, flexible membrane material having a plurality of pores is disclosed. In one embodiment, the pores have an unflexed exit aperture diameter in the range of about 0.5 to about 2 microns (preferably about 1 micron) and are positioned substantially uniformly in the material, preferably about 50 microns apart. The nozzle preferably has a conical or trumpet-shaped cross-section. In another aspect of the invention, the exit aperture of the nozzle is surrounded by an elevated area protruding above the substantially planar exit side of the membrane in order to prevent intrusion of liquid back into the nozzle. The nozzle can be used to form an aerosol containing a pharmaceutical composition from the exit side of the nozzle upon forcible application of the composition to the entrance side of the nozzle. This aerosol can be used to administer the pharmaceutical composition, for example, to the eye or to a selected portion of the respiratory tract. The nozzle is preferably a component of a container which holds a formulation of drug.

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