Cyclodextrin polymers for carrying and releasing drugs
Patent 6048736 Issued on April 11, 2000. Estimated Expiration Date: 
December 30, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 30, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorApplicationNo. 223055 filed on 12/30/1998US Classes:436/536, INVOLVING IMMUNE COMPLEX FORMED IN LIQUID PHASE436/507, Immune complex514/58Dextrin or derivativeExaminersPrimary: Stucker, JeffreyAssistant: Nelson, Brett Foreign Patent References
International ClassesG01N 033/536G01N 033/564 A01N 043/04 A61K 031/715 AbstractThis invention discloses methods for preparing compositions of cyclodextrin polymers for carrying drugs and other active agents. Methods are also disclosed for preparing cyclodextrin polymer carriers that release drugs under controlled conditions. The invention also discloses methods for preparing compositions of cyclodextrin polymer carriers that are coupled to biorecognition molecules for targeting the delivery of drugs to their site of action.The advantages of the water soluble (or colloidal) cyclodextrin polymer carrier are:(1) Drugs can be used that are designed for efficacy without conjugation requirements.(2) It will allow the use of drugs designed solely for efficacy without regard for solubility.(3) Unmodified drugs can be delivered as macromolecules and released within the cell.(4) Drugs can be targeted by coupling the carrier to biorecognition molecules.(5) Synthesis methods are independent of the drug to facilitate multiple drug therapies. |
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