U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Microfluidic devices and systems

Patent 6048498 Issued on April 11, 2000. Estimated Expiration Date: Icon_subject November 12, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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More ...

Inventor

Application

No. 190428 filed on 11/12/1998

US Classes:

422/99, Miscellaneous laboratory apparatus and elements, per se73/864.91, Sample holder204/451, Capillary electrophoresis204/452, With detailed detection204/600, Electrophoretic or electro-osmotic apparatus204/601, Capillary electrophoresis type204/603, With detailed detection system (e.g., including a light source and a camera, etc.)206/261, Casing formed of two hinged complementary covers206/263, Having retaining member215/395, Container support220/755, Specified gripping structure (i.e., the handle portion that is contacted by the hand)220/771, Handle is of one-piece construction with a container356/244, SAMPLE, SPECIMEN, OR STANDARD HOLDER OR SUPPORT (E.G., PLATES OR SLIDES)356/246, Fluid containers (e.g., cells or cuvettes)422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light422/100, Pipette or other volumetric fluid transfer means422/104, Holder, support, housing, or hood422/108Control element responds proportionally to a variable signal from a sensor

Examiners

Primary: Gulakowski, Randy
Assistant: Carrillo, Sharidan

Attorney, Agent or Firm

Foreign Patent References

  • WO 9604547 WO. 02/13/1996
  • WO 9702357 WO. 01/13/1997

International Class

B01L 003/00

Abstract

Microfluidic apparatus which include a planar device and polymeric holder assembly are provided. The polymeric holder assembly includes a cavity disposed through the holder, providing optical access to the top and bottom of the planar device when the device is mounted in the polymeric holder. The planar device includes microscale channels disposed within the device.

Other References

  • Dasgupta, P.K. et al., "Electroosmosis: A Reliable Fluid Propulsion System for Flow Injection Analysis," Anal. Chem. 66:1792-1798 (1994)
  • Jacobson, S.C. et al., "Fused Quartz Substrates for Microchip Electrophoresis," Anal. Chem. 67:2059-2063 (1995)
  • Manz, A. et al., "Electroosmotic pumping and electrophoretic separations for miniaturized chemical analysis systems," J. Micromech. Microeng. 4:257-265 (1994)
  • Ramsey, J.M. et al., "Microfabricated chemical measurement systems," Nature Med. 1:1093-1096 (1995)
  • Seiler, K. et al., "Planar Glass Chips for Capillary Electrophoresis: Repetitive Sample Injection, Quantitation, and Separation Efficiency," Anal. Chem. 65:1481-1488 (1993)
  • Seiler, K. et al., "Electroosmotic Pumping and Valveless Control of Fluid Flow within a Manifold of Capillaries on a Glass Chip," Anal. Chem. 66:3485-3491 (1994)
  • Young, J., "Lab on a Chip," Forbes Sep. 23, 199
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