Patent ReferencesCompositions, articles and mehtod for improving wound healing Collagen matrix/polymer film composite dressing Skin treatment composition Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution Use of protease nexin-I in wound dressings Nitrous oxide containing dermatological composition Cytoprotective wound healing compositions and methods for preparing and using same Bioadhesive-wound healing compositions and methods for preparing and using same Immunostimulating wound healing compositions and method for preparing and using same Mesh matrix wound dressing InventorAssigneeApplicationNo. 358777 filed on 07/22/1999US Classes:514/2, Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI514/458, Tocopherols (e.g., vitamin E, etc.)514/474Ascorbic acid or derivative (e.g., vitamin C, etc.)ExaminersPrimary: Henley, III, RaymondAttorney, Agent or FirmForeign Patent References
International ClassesA61K 038/00A61K 031/355 A61K 031/34 AbstractThe healing of wounds is enhanced by contacting the wound surfaces with a dressing of D-glucose polysaccharide obtained by hydrolysis of starch containing ascorbic acid, collagen type I and alpha-tocopherol acetate. The collagen type I, and the ascorbic acid in the dressing are the typical chemotactic agents of neutrophils, fibroblasts and/or endothelial cells. These combinations can be present in the dressing as a gel. The composition material can be applied to the wound as a particulate material such as a powder, or as material such as a gel, paste, dispersion, solution or syrup. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, severe cuts and abrasions which are commonly resistant to the natural healing process, may be treated with this composition. The application of this combination to open wounds greatly accelerates the rate of healing and reduces scarring. The invention includes an article useful in the therapy for surface wounds comprising the suspension of particles on non-adherent gauze and a bandage tape. | |