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Composition and method for enhancing wound healing

Patent 6046160 Issued on April 4, 2000. Estimated Expiration Date: Icon_subject July 22, 2019. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Compositions, articles and mehtod for improving wound healing
Patent #: 4837024
Issued on: 06/06/1989
Inventor: Michaeli

Collagen matrix/polymer film composite dressing
Patent #: 4841962
Issued on: 06/27/1989
Inventor: Berg ,   et al.

Skin treatment composition
Patent #: 4950688
Issued on: 08/21/1990
Inventor: Bowser, et al.

Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution
Patent #: 5133965
Issued on: 07/28/1992
Inventor: Fountain

Use of protease nexin-I in wound dressings
Patent #: 5196196
Issued on: 03/23/1993
Inventor: Scott, et al.

Nitrous oxide containing dermatological composition
Patent #: 5633284
Issued on: 05/27/1997
Inventor: Meyer

Cytoprotective wound healing compositions and methods for preparing and using same
Patent #: 5633285
Issued on: 05/27/1997
Inventor: Martin

Bioadhesive-wound healing compositions and methods for preparing and using same
Patent #: 5658956
Issued on: 08/19/1997
Inventor: Martin, et al.

Immunostimulating wound healing compositions and method for preparing and using same
Patent #: 5658957
Issued on: 08/19/1997
Inventor: Martin

Mesh matrix wound dressing
Patent #: 5676967
Issued on: 10/14/1997
Inventor: Williams, et al.

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Inventor

Assignee

Application

No. 358777 filed on 07/22/1999

US Classes:

514/2, Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI514/458, Tocopherols (e.g., vitamin E, etc.)514/474Ascorbic acid or derivative (e.g., vitamin C, etc.)

Examiners

Primary: Henley, III, Raymond

Attorney, Agent or Firm

Foreign Patent References

  • 138385 EP 04/12/1985

International Classes

A61K 038/00
A61K 031/355
A61K 031/34

Abstract

The healing of wounds is enhanced by contacting the wound surfaces with a dressing of D-glucose polysaccharide obtained by hydrolysis of starch containing ascorbic acid, collagen type I and alpha-tocopherol acetate. The collagen type I, and the ascorbic acid in the dressing are the typical chemotactic agents of neutrophils, fibroblasts and/or endothelial cells. These combinations can be present in the dressing as a gel. The composition material can be applied to the wound as a particulate material such as a powder, or as material such as a gel, paste, dispersion, solution or syrup. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, severe cuts and abrasions which are commonly resistant to the natural healing process, may be treated with this composition. The application of this combination to open wounds greatly accelerates the rate of healing and reduces scarring. The invention includes an article useful in the therapy for surface wounds comprising the suspension of particles on non-adherent gauze and a bandage tape.

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