Apparatus and method for combinatorial chemistry synthesis
Patent 6045755 Issued on April 4, 2000. Estimated Expiration Date: March 10, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
422/65, Means is conveyor and rack422/81, Automated system with sample fluid pressure transport means422/103, Valve or connector structure422/104, Holder, support, housing, or hood422/131, Organic polymerization422/134, Including plural sequential reaction stages436/43, AUTOMATED CHEMICAL ANALYSIS436/47, With conveyance of sample along a test line in a container or rack436/49, With treatment or replacement of aspirator element (e.g., cleaning, etc.)436/174, INCLUDING SAMPLE PREPARATION439/180CONTACT SEPARATION BY SNAP OR QUICK-BREAK ACTION
In a first embodiment, this invention includes an integrated robot apparatus for performing combinatorial chemistry synthesis protocols and having interchangeable work-stations, robot arm tools, and reaction vessels and reaction vessel arrays. The work-stations and tools are specialized to perform tasks necessary for the synthesis in a plurality of the reaction vessels grouped in a plurality of the reaction vessel arrays. Preferably, these elements function interchangeably because they have standardized sizes and conformation. The work-stations and tools include those for fluid dispensing or aspirating from individual reaction vessels or from all the reaction vessels in an array simultaneously. The reaction vessels can include, alternatively, stackable, ball-sealed reaction vessels, microtitre-like reaction vessel arrays, arrays of independent reaction vessels, valve-sealed reaction vessels, septum-sealed reaction vessels, and syringe reaction vessels. In alternative embodiments, this invention includes these work-stations, tools, reaction vessels and reaction vessel arrays in various combinations or sub-combinations either for use in partially integrated robots or for manual or standalone use.
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March 10, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
