Patent ReferencesImpotence ointment Dosage forms and method for ameliorating male erectile dysfunction Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses Patent #: 5874437 InventorAssigneeApplicationNo. 154052 filed on 09/16/1998US Classes:514/292, Plural ring nitrogens in the tricyclo ring system546/85The six-membered hetero ring shares ring members with the five-membered cyclo only (e.g., pyrido-indoles, etc.)ExaminersPrimary: Jones, Dwayne C.Assistant: Delacroix-Muirheid, C. Attorney, Agent or FirmInternational ClassA61K 031/44AbstractCarboline derivatives of formula (I) ##STR1## are potent and selective inhibitors of cyclic guanosine 3',5'-monophosphate specific phosphodiesterase (cGMP-specific PDE) and have utility in a variety of therapeutic areas where such inhibition is thought to be beneficial, including the treatment of cardiovascular disorders and erectile dysfunction. |
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