Carboline derivatives
Patent 6043252 Issued on March 28, 2000. Estimated Expiration Date: 
September 16, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 16, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesImpotence ointment Dosage forms and method for ameliorating male erectile dysfunction Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses Patent #: 5874437 InventorAssigneeApplicationNo. 154052 filed on 09/16/1998US Classes:514/292, Plural ring nitrogens in the tricyclo ring system546/85The six-membered hetero ring shares ring members with the five-membered cyclo only (e.g., pyrido-indoles, etc.)ExaminersPrimary: Jones, Dwayne C.Assistant: Delacroix-Muirheid, C. Attorney, Agent or FirmInternational ClassA61K 031/44AbstractCarboline derivatives of formula (I) ##STR1## are potent and selective inhibitors of cyclic guanosine 3',5'-monophosphate specific phosphodiesterase (cGMP-specific PDE) and have utility in a variety of therapeutic areas where such inhibition is thought to be beneficial, including the treatment of cardiovascular disorders and erectile dysfunction. |
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