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Administrable compositions and methods for magnetic resonance imaging

Patent 6042809 Issued on March 28, 2000. Estimated Expiration Date: Icon_subject August 12, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Magnetic resonance imaging using hyperpolarized noble gases
Patent #: 5545396
Issued on: 08/13/1996
Inventor: Albert, et al.

Method and system for producing polarized 129 Xe gas
Patent #: 5617860
Issued on: 04/08/1997
Inventor: Chupp, et al.

MR studies in which a paramagnetic gas is administered to a living patient
Patent #: 5694934
Issued on: 12/09/1997
Inventor: Edelman

Non-porous collagen sheet for therapeutic use, and the method and apparatus for preparing it
Patent #: 5785983
Issued on: 07/28/1998
Inventor: Furlan, et al.

Magnetic resonance imaging using hyperpolarized noble gases
Patent #: 5789921
Issued on: 08/04/1998
Inventor: Albert, et al.

Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents Patent #: 5922304
Issued on: 07/13/1999
Inventor: Unger

Inventors

Assignee

Application

No. 132763 filed on 08/12/1998

US Classes:

424/9.3, Magnetic imaging agent (e.g., NMR, MRI, MRS, etc.)424/9.37, Imageable halogen containing424/9.51, Liposome containing424/9.52Stable gas bubbles containing or intentional solubilized gas containing

Examiners

Primary: Hollinden, Gary E.

Attorney, Agent or Firm

Foreign Patent References

  • 97/29783 WO. 08/13/1997
  • 97/37239 WO. 10/13/1997

International Class

A61B 005/055

Foreign Application Priority Data

1997-08-12 EP

Abstract

The invention relates to the application of hyperpolarized gases to magnetic resonance imaging (MRI) of living subjects. The invention also concerns administrable compositions, formulations, methods of making the compositions and formulations and contrast agents involving hyperpolarized gases, as well as their use in MRI.

Other References

  • Song, Y et al., Journal of Magnetic Resonance series A 115(1):127-130 (1995)
  • Chawla, M.S., Proc. ISMRM 5th Scientific Meeting (1997) p. 211
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