U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Intravaginal drug delivery device

Patent 6039968 Issued on March 21, 2000. Estimated Expiration Date: Icon_subject June 22, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3545439

Polymeric diffusion matrix containing estradiol diacetate
Patent #: 4291014
Issued on: 09/22/1981
Inventor: Keith ,   et al.

Easily removable tampon
Patent #: 4300561
Issued on: 11/17/1981
Inventor: Kaczmarzyk ,   et al.

Channeled vaginal insert and method for treating urogenital disorders
Patent #: 5816248
Issued on: 10/06/1998
Inventor: Anderson, et al.

Intravaginal drug delivery devices for the administration of 17ଲ-oestradiol precursors Patent #: 5855906
Issued on: 01/05/1999
Inventor: McClay

Inventor

Assignee

Application

No. 102302 filed on 06/22/1998

US Classes:

424/433Depot, pellet, matrix, or suppository

Examiners

Primary: Azpuru, Carlos

Attorney, Agent or Firm

International Class

A61F 013/02

Foreign Application Priority Data

1997-06-24 GB

Abstract

The invention provides an intravaginal drug delivery system having a first intravaginal part comprising at least one active agent in a polymer matrix, said first part being provided in association with a second part comprising a removable polymer membrane arranged to absorb excess active agent. Use of a polymer membrane in this way serves to substantially reduce the initial high burst of active from the intravaginal part following administration. It also reduces the levels of release of active during the first few weeks of use. Also provided is an intravaginal drug delivery device comprising at least one active agent dispersed in a polymer matrix, wherein the concentration of active agent at the outer surface of the device at the time of use is not substantially higher than the concentration of the active agent in the remainder of the device.

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