U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Treatment of oppositional defiant disorder

Patent 6028070 Issued on February 22, 2000. Estimated Expiration Date: Icon_subject September 17, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Substituted morpholine derivatives and compositions
Patent #: 4229449
Issued on: 10/21/1980
Inventor: Melloni ,   et al.

Potentiation of drug response
Patent #: 5532268
Issued on: 07/02/1996
Inventor: Wong, et al.

Treatment of attention-deficit/hyperactivity disorder
Patent #: 5658590
Issued on: 08/19/1997
Inventor: Heiligenstein, et al.

Treatment of attention-deficit/hyperactivity disorder Patent #: 5696168
Issued on: 12/09/1997
Inventor: Heiligenstein, et al.

Inventor

Assignee

Application

No. 156289 filed on 09/17/1998

US Classes:

514/238.8, Chalcogen attached indirectly to the morpholine ring by acyclic nonionic bonding514/239.2, The chalcogen is bonded directly to two carbon atoms514/239.5, Carbocyclic ring attached indirectly to the morpholine ring by nonionic bonding514/438, The hetero ring is five-membered514/620, The nitrogen in R is an amino nitrogen attached indirectly to a ring by acyclic bonding514/649, Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chain514/651, Ether oxygen is part of the chain514/653Hydroxy, bonded directly to carbon, attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding (e.g., beta hydroxy phenethylamines, etc.)

Examiners

Primary: Krass, Frederick

Attorney, Agent or Firm

Foreign Patent References

  • 0 687 472 EP. 12/13/1995
  • WO 96 12485 WO. 05/13/1996

International Classes

A61K 031/535
A61K 031/38
A61K 031/165
A61K 031/135

Abstract

Norepinephrine reuptake inhibitors are used to treat oppositional defiant disorder.

Other References

  • Chemical Abstract 89:157222, "Comparison of Inhibition of Monoamine Uptake by Cocaine, Methylphenidate, and Amphetamine", 1978
  • Journal of Abnormal Child Psychology. Barkley, R.A. et al., Adolescents with attention deficit hyperactivity disorder: mother-adolescent interactions, family beliefs and conflicts, and maternal psychopathology Abstract, Jun. 1992, vol. 20, No. 3, pp. 263-288
  • Diagnostic and Statistical Manual of Developmental Disorders, Fourth Edition (DSM-IV)pp. 78-94
  • POPPER, C.W.: "Antidepressants in the treatment of attention-deficit/hyperactivity disorder" The Journal of Clinical Psychiatry, vol. 58, no. suppl. 13, 1997, pp. 14-29
  • Greydanus, D. E. et al.: "The rebellious adolescent: Evaluation and management of oppositional and conduct disorders" Pediatric Clinics of North America, vol. 44, no. 6, pp. 1457-148
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