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Maize and cauliflower apetalai gene products and nucleic acid molecules encoding same

Patent 6025483 Issued on February 15, 2000. Estimated Expiration Date: Icon_subject June 5, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Genetically modified plants having modulated flower development
Patent #: 5637785
Issued on: 06/10/1997
Inventor: Weigel

Genetically modified plants having modulated flower development Patent #: 5844119
Issued on: 12/01/1998
Inventor: Weigel

Inventor

Application

No. 655227 filed on 06/05/1996

US Classes:

536/23.6, Encodes a plant polypeptide435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)435/468, Introduction of a polynucleotide molecule into or rearrangement of a nucleic acid within a plant cell536/24.1, Non-coding sequences which control transcription or translation processes (e.g., promoters, operators, enhancers, ribosome binding sites, etc.)800/290The polynucleotide alters plant part growth (e.g., stem or tuber length, etc.)

Examiners

Primary: Fox, David T.

Attorney, Agent or Firm

Foreign Patent References

  • WO 96/19105 JP. 06/13/1996
  • 9405776 WO. 03/13/1994

International Classes

C12N 015/29
C12N 015/82

Abstract

The present invention provides a substantially purified nucleic acid molecule encoding a Brassica oleracea APETALA1 (AP1) gene product, Brassica oleracea var. botrytis AP1 gene product or a Zea mays AP1 gene product. The invention also provides a substantially purified Brassica oleracea AP1 gene product, a substantially purified Brassica oleracea var. botrytis AP1 gene product or a substantially purified Zea mays AP1 gene product in addition to an antibody that specifically binds such an AP1 gene product. In addtion, the invention provides an expression vector containing a nucleic acid molecule encoding a floral meristem identity gene product operably linked to a heterologous regulatory element. Kits for converting shoot meristem to floral meristem in an angiosperm and kits for promoting early reproductive development in a seed plant also are provided.

Other References

  • Alvarez et al., "Terminal flower: A Gene Affecting Inflorescence Development in Arabidopsis thaliana," Plant J. 2:103-116 (1992)
  • Anthony et al., "Cauliflower (Brassica oleracea var. botrytis L.) Curd Development: the Expression of Meristem Identity Genes," J. Experimental Botany 47:181-188 (1996)
  • Anthony et al., "Cloning and Sequence Analysis of a flo/lfy Homologue Isolated From Cauliflower (Brassica oleracea L. var. botrytis), "Plant Molecular Biology 22:1163-1166 (1993)
  • Anthony et al., "The cDNA Sequence of a Cauliflower apetala-1/squamosa Homolog," Plant Physiol. 108:441-442 (1995)
  • Bowman et al. "Control of Flower Development in Arabidopsis thaliana by Apetala1 and Interacting Genes," Development 119 :721-743
  • Chung et al., "Early Flowering and Reduced Apical Dominance Result From Ectopic Expression of a Rice MADS Box Gene," Plant Mol. Biol. 26:657-665 (1994)
  • Coen et al., "Floricaula: A Homeotic Gene Required for Flower Development in Antirrhinum majus," Cell 63:1311-1322 (1990)
  • Huijser et al., "Bracteomania, an Inflorescence Anomaly, is Caused by the Loss of Function of the MADS-box Gene Squamosa in Antirrhimun majus," Embo J. 11:1239-1249 (1992)
  • Kelly et al., "NFL, the Tobacco Homolog of Floricaula and Leafy, is Transcriptionally Expressed in Both Vegetative and Floral Meristems," Plant Cell 7:225-234 (1995)
  • Kempin et al., "Molecular Basis of the cauliflower Phenotype in Arabidopsis," Science 267:522-525 (1995)
  • Mandel et al., "Function and Regulation of the Arabidopsis Apetala1 Gene", poster presented at The Sixth International Meeting on Arabidopsis Research, Jun. 7-11, 1995
  • Mandel et al., "Molecular Characterization of the Arabidopsis Floral Homeotic Gene Apetala1,"Nature 360:273-277 (1992)
  • Mandel and Yanofsky, "A Gene Triggering Flower Formation in Arabidopsis,"Nature 377:522-524 (1995)
  • Mena et al., "A Characterization of the MADS-Box Gene Family in Maize," The Plant Journal 8 (6), 845-854 (1995)
  • Purugganan et al., "Molecular Evolution of Flower Development: Diversification of the Plant MADS-Box Regulatory Gene Family," Genetics 140:345-356 (1995 )
  • Putterill et al., "The Constans Gene of Arabidopsis Promotes Flowering and Encodes a Protein Showing Similarities to Zinc Finger Transcription Factors," Cell 80:847-857 (1995)
  • Rottmann et al., "Structure and Expression of a Leafy Homolog From Populus," Cell Biochem. Suppl. 17B:23 (1993)
  • Sommer et al., "Deficiens, a Homeotic Gene Involved in the Control of Flower Morphogenesis in Antirrhinum Majus: the Protein Shows Homology to Transcription Factors," The EMBO Journal 9:605-613 (1990)
  • Strauss et al., "Genetic Engineering of Reproductive Sterility in Forest Trees, " Molec. Breed. 1:5-26 (1995)
  • Weigel, "The Genetics of Flower Development: From Floral Induction to Ovule Morphogenesis," Annu. Rev. Genetics 29:19-39 (1995)
  • Weigel and Nilsson, "A Developmental Switch Sufficient for Flower Initiation in Diverse Plants," Nature 377:495-500 (1995)
  • Weigel et al., "Leafy Controls Floral Meristem Identity in Arabidopsis," Cell 69:843-859 (1992)
  • Yanofsky, "Floral Meristems to Floral Organs: Genes Controlling Early Events in Arabidopsis Flower Development," Annu. Rev. Plant Physiol. Plant Mol. Biol. 46:167-188 (1995)
  • Savidge et al., "Molecular Basis of the Cauliflower Phenotype", talk presented by Beth Savidge at The Six International Meeting on Arabidopsis Research, Jun. 7-11, 1995
  • Weigel and Nilsson, "Leafy Encodes a Developmental Switch", talk presented by Detlef Weigel at The Sixth International Meeting on Arabidopsis Research, Jun. 7-11, 1995
  • Newman et al. 1994. Plant Physiol. 106:1241-1255
  • Sasaki et al. 1994. Plant Journal 6(4):615-62
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