MR imaging using mutual interaction between different kinds of pools of nuclear spins
Patent 6023634 Issued on February 8, 2000. Estimated Expiration Date: 
March 20, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 20, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMagnetization transfer contrast and proton relaxation and use thereof in magnetic resonance imaging MR imaging apparatus using a devised MTC pulse waveform Patent #: 5682891 InventorsApplicationNo. 618859 filed on 03/20/1996US Classes:600/410, Magnetic resonance imaging or spectroscopy324/307, Using a nuclear resonance spectrometer system324/309To obtain localized resonance within a sampleExaminersPrimary: Smith, Ruth S.Attorney, Agent or FirmInternational ClassA61B 005/055Foreign Application Priority Data1995-03-20 JPAbstractIn addition to the known MT (magnetization transfer) effect, an RMT (reverse MT) is newly found, which increases a detected MR signal strength. Both the MT and RMT effects can be explained with mutual interaction, such as phenomena of chemical exchange and/or cross relaxation, acted between a pool of water proton spins and another pool of macromolecule proton spins, for example, within an object. In order to enhance the MT or RMT effect, the frequency bandwidths of RF pulses, such as a 90° RF exciting pulse in a SE or FSE method, an inversion pulse in a FLAIR or fast FLAIR method, and others, are controlled. To enhance the MT effect, the bandwidth is controlled into a wider value (approx. more than 1250 Hz) than the normally (conventionally) used bandwidth, while to obtain the RMT effect, the bandwidth is controlled into a narrower value (approx. less than 1000 Hz) than the normally used bandwidth. Actively controlling the MT or RMT effect permits changed image contrast in MR imaging.Other References
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