Compositions and methods for stimulating bone growth
Patent 6022887 Issued on February 8, 2000. Estimated Expiration Date: 
December 12, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 12, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones Methods for reducing bone loss using centchroman derivatives Methods for inhibiting bone loss with bis-pyrone oxovanadium compounds Lactone compound and process of production thereof Patent #: 5604257 Inventors
AssigneeApplicationNo. 989862 filed on 12/12/1997US Classes:514/451, The hetero ring is six-membered514/460, Chalcogen bonded directly to ring carbon of the hetero ring549/273The lactone ring is six-memberedExaminersPrimary: Kunz, Gary L.Assistant: Moran, Marjorie A. Attorney, Agent or FirmInternational ClassesA01N 043/16C07D 309/00 AbstractCompounds of the formula ##STR1## wherein X in each of formulas (1) and (2) represents a substituted or unsubstituted alkylene, alkenylene, or alkynylene linker of 2-6C;Y represents one or more carbocyclic or heterocyclic rings; when two or more rings are present in Y, they may optionally be fused; andR' represents a cation, H or a substituted or unsubstituted alkyl group of 1-6C; andthe dotted lines represent optional π-bonds,promote bone formation and are thus usefull in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation.Other References
|
| ||||||||||||||
