Hydroalcoholic compositions for transdermal penetration of pharmaceutical agents

Patent 6019997 Issued on February 1, 2000. Estimated Expiration Date:

January 9, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

2054989

2153143

2678902

3131152

3131153

3395214

3415939

3840465

Potentiated medicaments
Patent #: 4006218
Issued on: 02/01/1977
Inventor: Sipos

Film-forming alcoholic microbicidal teat dip and method of use thereof
Patent #: 4199564
Issued on: 04/22/1980
Inventor: Silver , et al.

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Inventors

Assignee

Minnesota Mining and Manufacturing Co.

Application

No. 781097 filed on 01/09/1997

US Classes:

424/449, Transdermal or percutaneous514/937, DISPERSION OR EMULSION514/946, PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)514/947Topical application

Examiners

Primary: Brouillette, Gabrielle

Attorney, Agent or Firm

Sprague; Robert W., Hohenshell; Jeffrey J.

Foreign Patent References

B-72440/87 AU. 11/13/1987
0 014 502 A1 EP. 08/13/1980
0 223 681 A1 EP. 05/13/1987
0 260 641 A2 EP. 03/13/1988
0 289 160 A1 EP. 04/13/1988
0 381 618 A1 EP. 08/13/1990
0 451 949 A1 EP. 10/13/1991
0 522 624 A1 EP. 01/13/1993
0 689 767 A2 EP. 01/13/1996
0 745 389 A1 EP. 12/13/1996
788 811 FR. 10/13/2012
2 406 438 FR. 05/13/1979
34 16 777 A1 DE. 11/13/1985
3632030 A1 DE. 03/13/1988
80 92 078 JP. 04/13/1996
1 527 781 GB. 10/13/1978
93/07903 WO. 04/13/1993
WO 94/13354 WO. 06/13/1994
95/03772 WO. 02/13/1995
WO 97/00667 WO. 01/13/1997

International Class

A61F 013/00

Abstract

Hydroalcoholic compositions useful for the enhancement of the transdermal delivery of a pharmaceutical agent, methods of preparation, transdermal delivery systems, and methods of delivering the pharmaceutical agent are provided. The composition includes a lower alcohol and water in a weight ratio of at least about 20:80, a pharmaceutical agent, and an emulsifier system.

Other References

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