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US Patent 6017963 - Formulation for intranasal administration
US Patent Issued on January 25, 2000
Estimated Patent Expiration Date:
November 14, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
November 14, 2015Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractA dosage form for intranasal and/or inhalation administration of an analgesic having low opioid receptor binding activity to a warm blooded animal, that includes a pharmaceutically effective amount of the analgesic. A preferred analgesic is tramadol, a tramadol and/or a pharmaceutically acceptable salt, metabolite or derivative thereof. Methods of making and using the formulation according to the invention are also provided.Other References
| InventorsAssigneeApplicationNo. 557279 filed on 11/14/1995US Classes:514/646Benzene ring containingField of Search514/646Benzene ring containingExaminersPrimary: MacMillan, Keith D.Attorney, Agent or FirmUS Patent References3652589, 4440777, Use of eucalyptol for enhancing skin permeation of bio-affecting agentsIssued on: 04/03/1984 Inventor: Zupan4464378, Method of administering narcotic antagonists and analgesics and novel dosage forms containing same Issued on: 08/07/1984 Inventor: Hussain4624965, Novel method of administering anti-nausea and anti-emetic pharmaceutical agents and novel dosage forms containing same Issued on: 11/25/1986 Inventor: Wenig4729997, Novel method of administering meclizine type pharmaceutical agents and novel dosage forms containing same Issued on: 03/08/1988 Inventor: Wenig4749700, Novel methods of administering antihistamines, antinausea and antiemetic pharmaceutical agents and novel dosage forms containing same Issued on: 06/07/1988 Inventor: Wenig4778810, Nasal delivery of caffeine Issued on: 10/18/1988 Inventor: Wenig , et al.4880813, Method of treatment for allergic rhinitis Issued on: 11/14/1989 Inventor: Frost4973596, Method of administering a narcotic analgesic and dosage forms therefor Issued on: 11/27/1990 Inventor: Cohen5066648, Pyroglutamic acid esters used as dermal penetration enhancers for drugs Issued on: 11/19/1991 Inventor: Alexander, et al.5204119, External preparation comprising calcium silicate Issued on: 04/20/1993 Inventor: Shiobara, et al.5223541, Tramadol N-oxide material, enantiomers and compositions thereof, and their use Issued on: 06/29/1993 Inventor: Maryanoff, et al.5336691, Composition comprising a tramadol material and acetaminophen and its use Issued on: 08/09/1994 Inventor: Raffa, et al. 5446070, 5451408, Pain management with liposome-encapsulated analgesic drugs Issued on: 09/19/1995 Inventor: Mezei, et al.5468744Composition comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use Issued on: 11/21/1995 Inventor: Raffa, et al. Foreign Patent References
International ClassA61K 031/135 |
