Method and apparatus for background correction in photoluminescent analysis
Indirect colorimetric detection of an analyte in a sample using ratio of light signals
Tetrabenztriazaporphyrin reagents and kits containing the same
Method for detecting nucleic acid amplification using self-quenching fluorescence probe
Detection of nucleic acid amplification
Selective amplification system using Q-ଲ replicase
Method for detection of nucleic acid using total internal reflectance
Fluorerscence polarization detection of nucleic acid amplication Patent #: 5593867
ApplicationNo. 046114 filed on 03/20/1998
US Classes:435/6, Involving nucleic acid422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light422/82.08, Fluorescence422/82.09, Absorbance or transmittance435/91.2Acellular exponential or geometric amplification (e.g., PCR, etc.)
ExaminersPrimary: Horlick, Kenneth R.
Attorney, Agent or Firm
Foreign Patent References
International ClassesC12Q 001/68
AbstractAn apparatus is provided which includes a sample holder for holding a reaction chamber which includes an optical interface, a fiber optic cable for delivering an excitation beam to a sample housed within the reaction chamber and for receiving light emitted by the sample, and a lens co-axially disposed with the fiber optic cable and positioned outside the reaction chamber for focusing the excitation beam through the optical interface and within a volume of the sample and for collecting and transmitting to the fiber optic cable light emitted within the volume of the sample.