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Method for the production of 1,3-propanediol by recombinant microorganisms

Patent 6013494 Issued on January 11, 2000. Estimated Expiration Date: Icon_subject November 12, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism Patent #: 5686276
Issued on: 11/11/1997
Inventor: Laffend, et al.

Inventors

Assignee

Application

No. 968563 filed on 11/12/1997

US Classes:

435/158, Polyhydric435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/252.3, Transformants (e.g., recombinant DNA or vector or foreign or exogenous gene containing, fused bacteria, etc.)435/252.33, Escherichia (e.g., E. coli, etc.)435/254.21Saccharomyces

Examiners

Primary: Railey, II, Johnny F.

Foreign Patent References

  • 373 230 EP. 06/13/1990
  • 3734 764 DE. 05/13/1989
  • WO 96 35796 WO. 11/13/1996

International Classes

C12P 007/18
C12N 001/19
C12N 001/21
C12N 015/31

Abstract

Recombinant organisms are provided comprising genes encoding glycerol-3-phosphate dehydrogenase, glycerol-3-phosphatase, glycerol dehydratase and 1,3-propanediol oxidoreductase activites useful for the production of 1,3-propanediol from a variety of carbon substrates.

Other References

  • R. Daniel et al., Journal of Bacteriology, 177, No. 8, 2151-2156, Apr. 1, 1995
  • T. Tobimatsu et al., Journal of Biological Chemistry, 271, No. 37, 22352-22357, Sep. 13, 1996
  • Ben-Amotz et al., Experientia 38, 49-52, 1982
  • Albertyn et al., Mol. Cell. Biol., 14, 4135-4144, 1994
  • Wang et al., J. Bact., 176, 7091-7095, 1994
  • Larason et al., Mol. Microbiol., 10, 1101, 1993
  • Mol. Cell. Biol. 14, 4135, 1994
  • Appl. Biochem. Biotech. 34, 149, 1992
  • Norbeck et al., J. Biol. Chem., 271, 13875, 1996
  • Veiga DA Cunha et al., J. Bacteriol., 174, 1013, 1992
  • Steib et al., Arch. Microbiol, 140, 139, 1984
  • I-T. Tong, Ph.D., Thesis, University of Wisconsin-Madison, 199
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