Propoxyphene derivatives for immunoassay reagents
Patent 6004824 Issued on December 21, 1999. Estimated Expiration Date: 
July 2, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 2, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPolypeptide propoxyphene derivatives for immunoassay reagents Compounds for enzyme amplification assay Haptens and tracers for immunoassays for propoxyphene Quaternary ammonium immunogenic conjugates and immunoassay reagents Patent #: 5492841 InventorAssigneeApplicationNo. 886800 filed on 07/02/1997US Classes:436/533, Carrier is water suspendible particles (e.g., latex, etc.)435/188, Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate436/544, Producing labeled antigens436/545, Radioactive label436/546, Fluorescent label436/815, TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS530/405, Nitrogen containing reactant530/807HAPTEN CONJUGATED WITH PEPTIDE OR PROTEINExaminersPrimary: Ceperley, Mary E.Attorney, Agent or FirmForeign Patent References
International ClassesG01N 033/533G01N 033/534 G01N 033/535 C07K 017/08 AbstractThe present invention provides hapten derivatives that are useful for the preparation of antigenic, antibody and label reagents having superior performance characteristics for use in immunoassays for the detection of d-propoxyphene and d-nor-propoxyphene. In the present invention the propoxyphene nucleus is derivatized out of the nitrogen center to form an aminoalkyl -carboxyl, or -hydroxyl haptenic derivative. The resulting hapten can then be further modified at the now functionalized position off the nitrogen for linking to an appropriate antigenic or labeling group to provide reagents for propoxyphene immunoassays having excellent sensitivity and selectivity for both d-propoxyphene and d-nor-propoxyphene.Other References
Field of SearchStablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugateHAPTEN CONJUGATED WITH PEPTIDE OR PROTEIN Nitrogen containing reactant Producing labeled antigens Radioactive label Fluorescent label Carrier is water suspendible particles (e.g., latex, etc.) TEST FOR NAMED COMPOUND OR CLASS OF COMPOUNDS |
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