Multi-layered osmotic device
May 29, 2018. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesLaminated osmotic system for dispensing beneficial agent Employment of enteric coated IgA for hypoproteinemia in intestinal infectious diseases Osmotic system with instant drug availability Osmotic system with instant drug availability Pseudoephedrine dosage form Pseudoephedrine brompheniramine therapy Dosage form for delivering soluble or insoluble drugs Controlled release formulation for water soluble drugs in which a passageway is formed in situ Controlled release drug delivery device Patent #: 5681584 InventorsAssigneeApplicationNo. 086871 filed on 05/29/1998US Classes:424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/468, Sustained or differential release type424/472, Layered unitary dosage forms424/474, Coated pills or tablets424/475, Organic coatings424/476, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof (e.g., chocolate)424/479, Containing polysaccharide (e.g., sugar, etc.)424/482Containing solid synthetic polymersExaminersPrimary: Page, Thurman K.Assistant: Channavajjala, Lakshmi Attorney, Agent or FirmInternational ClassesA61K 009/22A61K 009/24 AbstractThe present invention provides a simple and improved multi-layered osmotic device (1) that is capable of delivering a first active agent in an outer lamina (2) to one environment of use and a second active agent in the core (5) to another environment of use. Particular embodiments of the invention provide osmotic devices in which the first and second active agents are similar or dissimilar. An erodible polymer coat (3) between an internal semipermeable membrane (4) and a second active agent-containing external coat (2) comprises poly(vinylpyrrolidone)-(vinyl acetate) copolymer. This particular erodible polymer results in an improved multi-layered osmotic device possessing advantages over related devices known in the art. The active agent in the core (5) is delivered through a pore (6) containing an erodible plug (7). The osmotic device (1) can be coated by a final finish coat (8).Field of SearchSustained or differential release typeLayered unitary dosage forms With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.) Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof (e.g., chocolate) Containing polysaccharide (e.g., sugar, etc.) Containing solid synthetic polymers Coated pills or tablets Organic coatings | |
