U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method for detecting arthropods

Patent 5997846 Issued on December 7, 1999. Estimated Expiration Date: Icon_subject November 17, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Multi-function light device
Patent #: 4380790
Issued on: 04/19/1983
Inventor: Saferstein ,   et al.

Method to detect fungi and yeasts
Patent #: 5004699
Issued on: 04/02/1991
Inventor: Winters

Anti-lice treatment compositions
Patent #: 5292504
Issued on: 03/08/1994
Inventor: Cardin, et al.

Apparatus and method for immediate diagnosis of vaginal yeast infections
Patent #: 5353803
Issued on: 10/11/1994
Inventor: Cerra

5547665

Screen for inhibitors of chitinase
Patent #: 5561051
Issued on: 10/01/1996
Inventor: Silverman

Diagnosis of fungal infections with a chitinase Patent #: 5587292
Issued on: 12/24/1996
Inventor: Laine, et al.

Inventors

Assignee

Application

No. 971384 filed on 11/17/1997

US Classes:

424/9.6, Diagnostic or test agent produces in vivo fluorescence424/1.11, RADIONUCLIDE OR INTENDED RADIONUCLIDE CONTAINING; ADJUVANT OR CARRIER COMPOSITIONS; INTERMEDIATE OR PREPARATORY COMPOSITIONS424/1.17, Attached to or within viable or inviable whole micro-organism, cell, virus, fungus or specified sub-cellular structure thereof (e.g., platelet, red blood cell)424/9.1IN VIVO DIAGNOSIS OR IN VIVO TESTING

Examiners

Primary: Hollinden, Gary E.
Assistant: Joneson, Dameron

Attorney, Agent or Firm

Foreign Patent References

  • WO/9217786 WO. 10/12/1992

International Classes

A61K 049/00
G01N 031/00
G01N 033/48

Abstract

The present invention provides a method for detecting chitin-containing organisms on an area of a person or animal by contacting the particular area with a dye that is capable of biding to chitin and emitting fluorescence upon exposure to light. If a chitin-containing organism is present in the treated area, the chitin of the organism will bind the dye and, upon exposure to light, the chitin-containing organisms may be visualized and removed. Also provided by the present invention are solutions and suspensions that contain a dye capable of binding to a chitin-containing organism and emitting florescence upon exposure to light. The solutions and suspensions provided herein may be in the form of a shampoo, cream, lotion or detergent for the detection of chitin-containing organisms present in body hair, on the skin, clothing or the fur of animals. The solutions and suspensions may also be in a form suitable for spraying on clothes, as well as on the hair, skin and fur. Further provided by the present invention are kits comprising a solution or suspension that contains a dye capable of binding to a chitin-containing organism and a source of light that emits a wavelength capable of emitting fluorescence of the dye upon exposure to the light.

Other References

  • J. Vavra, et al., Staining of Microsporidian Spores by Optical Brighteners with remarks on the use of Brighteners for the Diagnosis of Aids Associated Human Microsporidioses, Folia Parasitologica, pp. 267-272 (1993)
  • Sutphin, et al.,Improved detection of Oculomycoses using induced fluorescence with celluflor, Opthalmology, 416-417, (1996)
  • Conteas, et al., Fluorescence Techniques for Diagnosing Intestinal Microsporidiosis in Stool, Enteric Fluid and Biopsy Specimens from Acquired Immunodeficiency Syndrome patients with chronic diarrhea, Arch Pathol. Lab. Med., vol. 120, Sep. 1996
  • Hegeage, Jr., et al., Use of Calcoflour White in Clinical Mycology, Laboratory Medicine, vol. 15, No. 2, Feb. 1984, pp. 109-112
  • Hoffgen, et al., The use of Funguigual A as a fluorescent dye in Medical Mycology, Aktuel-Dermatol., vol. 15 No. 7, 1989, pp. 216-20 (English Abstract only)
  • Hejtmanek, et al., Fluorescence Microscopy detection of Mycopathogens using Rylux BSU, Cesk Patol, 1989, Nov. 25(4) : 244-50 (English Abstract only)
  • Raclavsky, et al., Quantitative determination of yeast in sputum--a direct microscopy method, Cesk Epidemiol Mikrobiol Immunol, 1989 May; 38(3) : 161-6 (English Abstract only)
  • Costello, "This Gizmo Could Just Bring Out a Little Compulsiveness in Us All," Wall Street Journal, Oct. 13, 1998, Section B, P. 1
  • Oswald, et al., Quantitative fluorometric analysis of plant and microbial chitosanases, Anal . Biochem. 1992 Jul.; 204(1) : 40-6
  • Carrano, et al., Dansyl N-acetyl glucosamine as a precursor of fluorescent chitin: a method to detect fungal cell wall inhibitors, J. Antibiot (Tokyo)1997 Feb.; 50(2): 177-9
  • Trudel, et al., Detection of chitin deacetylase activity after polyaciylamide gel electrphoresis, Anal. Biochem. 1990 Sep.; 189(2) : 249-253
  • Borg-Von Zepelin, Fluorescence assay for the detection of adherent candida yeasts to target cells in microtest plates, Mycoses1995 Sep.-Oct.: 38(9-10): 339-347
  • Dox et al (1993), The Harper Collins Illustrated Medical Dictionary, pp. 96,177,253,276, 336, 480, 53
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$18.95more info
 
Sign InRegister
Username  
Password   
forgot password?