Method of stabilizing pharmaceutical preparations comprising digestive enzyme mixtures
Patent 5993806 Issued on November 30, 1999. Estimated Expiration Date: 
August 22, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 22, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPreparing pancreatin Stabilization of internally administered pancreatic lipase Continuous process of producing pancreatin and product thereof Novel enzyme particles and their preparation Patent #: 4242219 InventorAssigneeApplicationNo. 916325 filed on 08/22/1997US Classes:424/94.3, Stabilized enzymes or enzymes complexed with nonenzyme (e.g., liposomes, etc.)424/94.2, Multienzyme complexes or mixtures of enzymes424/94.21, Pancreatin424/428, Bioerrodable, resorbable, or dissolving424/550, Digestive system (e.g., salivary gland, etc.)424/556PancreasExaminersPrimary: Lankford, Leon B. Jr.Assistant: Tate, Christopher R. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 038/54A61K 035/39 A61K 035/37 A61F 002/00 Foreign Application Priority Data1996-08-28 DEAbstractThe use of complex lipids, especially lecithin, as additives to stabilize water-soluble pharmaceutical preparations of digestive enzyme mixtures containing lipases and proteases, especially pancreatin-containing digestive enzyme mixtures, which are suitable for preparing aqueous solutions for continuous introduction into the gastrointestinal tract by means of a tube, against a decrease in lipolytic activity under the influence of moisture.Other References
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