Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof
Patent 5990113 Issued on November 23, 1999. Estimated Expiration Date: 
December 16, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 16, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDiphenylpropanamines, compositions thereof and use thereof Aminobenzenesulfonic acid derivatives Polymorphic form of a tachykinin receptor antagonist Benzimidazoles and imidazopyridines as central nervous system agents Patent #: 5486517 InventorsAssigneeApplicationNo. 767062 filed on 12/16/1996US Classes:514/255.03, Carbocyclic ring bonded directly to the piperazine ring514/218, Hetero ring is seven-membered consisting of two nitrogens and five carbon atoms540/575, The nitrogens are in the 1,4-positions of the hetero ring544/392, Phenyl or naphthyl bonded directly to ring nitrogen of the piperazine ring544/394, The other ring nitrogen has a substituent which includes chalcogen single bonded to acyclic carbon544/395The other ring nitrogen is unsubstituted or alkyl substituted only, or salt thereofExaminersPrimary: Bernhardt, EmilyAttorney, Agent or FirmForeign Patent References
International ClassesA61K 031/495A61K 031/55 C07D 295/096 C07D 243/08 Foreign Application Priority Data1995-12-15 JPAbstractA monohydrate of an aminobenzenesulfonic acid derivative represented by the following formula (I), for example, 2-(1-piperazinyl)-5-methylbenzenesulfonic acid, is substantially free from weight change due to moisture absorption and can be weighed accurately in manufacturing a pharmaceutical composition for the treatment of heart diseases comprising said monohydrate. ##STR1##Other References
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