InventorsAssigneeApplicationNo. 913477 filed on 09/15/1997US Classes:424/234.1, Bacterium or component thereof or substance produced by said bacterium (e.g., Legionella, Borrelia, Anaplasma, Shigella, etc.)424/93.4, Bacteria or actinomycetales424/255.1, Pasteurella (e.g., Pasteurella multocida, Pasteurella hemolytica, etc.)435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/69.3, Antigens435/71.1Using a micro-organism to make a protein or polypeptideExaminersPrimary: Housel, James C.Assistant: Devi, S. Attorney, Agent or FirmInternational ClassesA61K 039/02A61K 039/102 A01N 063/00 C12P 021/06 Foreign Application Priority Data1995-03-13 GBAbstractA method of protecting a human or animal body from the effects of infection with Y. pestis is provided comprising administering to the body a vaccine including Yersinia pestis V antigen and Yersinia pestis F1 antigens or a protective epitopic part of each of these in a form other than whole Y. Pestis organisms. Preferably the antigens are administered in the form of a live vaccine or as recombinantly produced isolated and/or purified proteins. DNA encoding the whole or part of the F1 antigen and DNA encoding the whole or part of the V antigen may be used directly as a agnetic vaccine.Other References
Field of SearchBacterium or component thereof or substance produced by said bacterium (e.g., Legionella, Borrelia, Anaplasma, Shigella, etc.)Genetically modified micro-organism, cell, or virus (e.g., transformed, fused, hybrid, etc.) Bacteria or actinomycetales Fusion protein or fusion polypeptide (i.e., expression product of gene fusion) Pasteurella (e.g., Pasteurella multocida, Pasteurella hemolytica, etc.) Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI Recombinant DNA technique included in method of making a protein or polypeptide Antigens Using bacteria or actinomycetales Using a micro-organism to make a protein or polypeptide Encodes a microbial polypeptide |
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