U.S. patents available from 1976 to present.
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Vaccines for plague

Patent 5985285 Issued on November 16, 1999. Estimated Expiration Date: Icon_subject September 15, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Assignee

Application

No. 913477 filed on 09/15/1997

US Classes:

424/234.1, Bacterium or component thereof or substance produced by said bacterium (e.g., Legionella, Borrelia, Anaplasma, Shigella, etc.)424/93.4, Bacteria or actinomycetales424/255.1, Pasteurella (e.g., Pasteurella multocida, Pasteurella hemolytica, etc.)435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/69.3, Antigens435/71.1Using a micro-organism to make a protein or polypeptide

Examiners

Primary: Housel, James C.
Assistant: Devi, S.

Attorney, Agent or Firm

International Classes

A61K 039/02
A61K 039/102
A01N 063/00
C12P 021/06

Foreign Application Priority Data

1995-03-13 GB

Abstract

A method of protecting a human or animal body from the effects of infection with Y. pestis is provided comprising administering to the body a vaccine including Yersinia pestis V antigen and Yersinia pestis F1 antigens or a protective epitopic part of each of these in a form other than whole Y. Pestis organisms. Preferably the antigens are administered in the form of a live vaccine or as recombinantly produced isolated and/or purified proteins. DNA encoding the whole or part of the F1 antigen and DNA encoding the whole or part of the V antigen may be used directly as a agnetic vaccine.

Other References

  • FEMS Immunology and Medical Microbiology, 12 (3-4), 1995 223-230., XP000573083 Williamson E D et al: "A new improved sub-unit vaccine for plague: The basis of protection" see the whole document
  • Leary S E C et al: "Expression of Yersinia pestis V antigen in attenuated Salmonella typhimurim: Development of a novel vaccine for plague", Karger AG, 13 (0). 1995. 216-217., Basel, Switzerland XP000572863 in Ravagnan G & Chiesa C (eds): Yersiniosis: Present and Future
  • Infection and Immunity, vol. 63, No. 2, Feb. 1995, Washington US, pp. 563-568, XP002006749 Oyston P C F et al.: "Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against palgue" cited in the application see the whole document
  • Infection and Immunity, vol. 62, No. 10, Oct. 1994, Washington US, pp. 4192-4201, XP002006750 Motin V L et al.: "Passive immunity to Yersiniae mediated by anti-recombinant V antigen and protein A-V antigen fusion peptide" see the whole document
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