U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method and apparatus for administering analgesics, and method for making same device

Patent 5980927 Issued on November 9, 1999. Estimated Expiration Date: Icon_subject January 2, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Drug delivery devices comprising erodible polymer and erosion rate modifier
Patent #: 4346709
Issued on: 08/31/1982
Inventor: Schmitt

Long-term sustained-release preparation
Patent #: 4774091
Issued on: 09/27/1988
Inventor: Yamahira ,   et al.

In vivo delivery of neurotransmitters by implanted, encapsulated cells
Patent #: 4892538
Issued on: 01/09/1990
Inventor: Aebischer, et al.

Cyclodextrin complexes for neuraxial administration of drugs
Patent #: 5180716
Issued on: 01/19/1993
Inventor: Yaksh, et al.

Controlled drug delivery using polymer/pluronic blends
Patent #: 5330768
Issued on: 07/19/1994
Inventor: Park, et al.

Implantable therapy systems and methods Patent #: 5487739
Issued on: 01/30/1996
Inventor: Aebischer, et al.

Inventors

Assignee

Application

No. 775528 filed on 01/02/1997

US Classes:

424/425, Diffusion barrier is matrix424/423, Surgical implant or material424/424, Membrane or diffusion barrier424/426, Errodable, resorbable, or dissolving514/772.3, Solid synthetic organic polymer604/890.1CONTROLLED RELEASE THERAPEUTIC DEVICE OR SYSTEM

Examiners

Primary: Azpuru, Carlos

Foreign Patent References

  • WO 94/01166 WO 01/13/1994

International Classes

A61F 002/02
A61K 009/22
A61K 047/30

Abstract

A device and method is disclosed for continuously administering an analgesic to the neuraxis of an organism. The device comprises a polymeric matrix body loaded with the analgesic. The body is implanted in the neuraxis where the analgesic diffuses into the neuraxis.

Other References

  • "Controlled Releases of ACNU For Brain Tumor and Of Morphine For Anesthesia," I. Kaetsu, et al., Proceed. Intern. Symp. Control. Rel. Bioact. Mater. 21:527-8 (1994)
  • "Biodegradable Polymers For Controlled Delivery of Chemotherapy With and Without Radiation Therapy in the Monkey Brain", by Henry Brem, M.D. et al., in J. Neurosurg., Feb. 1994, vol. 80, pp. 283-290
  • "Interstitial Taxol Delivered from a Biodegradable Polymer Implant against Experimental Malignant Glioma", by Kevin A. Walter et al., in Cancer Research, Apr. 15, 1994, vol. 54, pp. 2207-221
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