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Process for cleaning bone grafts using centrifugal force and bone grafts produced thereby

Patent 5977432 Issued on November 2, 1999. Estimated Expiration Date: Icon_subject June 9, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3841909

Preparation of bone for transplantation
Patent #: 5333626
Issued on: 08/02/1994
Inventor: Morse, et al.

Preparation of bone for transplantation
Patent #: 5513662
Issued on: 05/07/1996
Inventor: Morse, et al.

Method for sterilizing bone grafts
Patent #: 5591398
Issued on: 01/07/1997
Inventor: Knaepler, et al.

Process for treating bone tissue and corresponding implantable biomaterials
Patent #: 5725579
Issued on: 03/10/1998
Inventor: Fages, et al.

Process for removal of lumen fillers and other soluble residues from hollow filaments
Patent #: 5779815
Issued on: 07/14/1998
Inventor: Breidohr, et al.

Articular cartilage heterografts
Patent #: 5782915
Issued on: 07/21/1998
Inventor: Stone

Ultrasonic cleaning of allograft bone
Patent #: 5797871
Issued on: 08/25/1998
Inventor: Wolfinbarger, Jr.

Process for cleaning large bone grafts and bone grafts produced thereby Patent #: 5820581
Issued on: 10/13/1998
Inventor: Wolfinbarger, Jr.

Inventors

Application

No. 871601 filed on 06/09/1997

US Classes:

128/898, Methods623/923Bone

Examiners

Primary: Yu, Mickey
Assistant: Jackson, Suzette J.

Attorney, Agent or Firm

International Class

A61M 031/100

Abstract

A process for removing essentially all bone marrow from a cut bone graft and the cut bone graft produced thereby. A large substantially intact bone is selected and excess cartilage and associated soft tissues are removed from the surface of the bone. The bone is left whole or may be cut into appropriate smaller pieces constituting cut grafts and bone marrow is removed from the cancellous bone spaces of the small cut grafts through the application of centrifugal force. Prior to and/or following the application of centrifugal force, the bone graft may optionally be pretreated with one or more decontaminating agents, and/or solubilizing agents.

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