U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Use of thermochromic liquid crystals in reflectometry based diagnostic methods

Patent 5972715 Issued on October 26, 1999. Estimated Expiration Date: Icon_subject December 23, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Liquid crystal film laminate
Patent #: 4310577
Issued on: 01/12/1982
Inventor: Davison ,   et al.

Analytical assay
Patent #: 5328852
Issued on: 07/12/1994
Inventor: Blackwood, et al.

5547283

Inventors

Assignee

Application

No. 773269 filed on 12/23/1996

US Classes:

436/164, OPTICAL RESULT374/161, Change of optical property374/162, Color422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light422/82.09, Absorbance or transmittance435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/25, Involving oxidoreductase436/46, With sample on test slide436/63, BIOLOGICAL CELLULAR MATERIAL TESTED436/165, With claimed manipulation of container to effect reaction or use of container of claimed optical structure436/169With reagent in absorbent or bibulous substrate

Examiners

Primary: Warden, Jill
Assistant: Carrillo, Sharidan

Attorney, Agent or Firm

Foreign Patent References

  • 0851229 EP. 07/13/1998

International Class

G01N 021/00

Abstract

A method for improving the accuracy of temperature sensitive diagnostic assays which are carried out using reflectance spectrometers to detect color changes in a solid test system which has been contacted with a fluid test system suspected of containing an analyte whose presence and/or concentration is being sought. The method involves determining the temperature of the solid test material by measuring the reflectance of a thermochromic liquid crystal in close proximity to the solid test material and correcting the result of the assay for a change in temperature from a pre-selected nominal temperature.

Other References

  • Kubo et al "Temperature dependency of optical properties of thermochromic materials". Netsu Bussei (1997), 11(2), 39-45 Abstract only, 1997
  • Nagai, Hirotoshi "Indicator for anesthetic gases by means of cholesteric liquid crystal". Fukushima Igaku Zasshi, 30(5/6) 357-64. Abstract only, 198
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