Dynamic particle size control for aerosolized drug delivery
Patent 5957124 Issued on September 28, 1999. Estimated Expiration Date: 
September 27, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 27, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3157179 3187748 3456646 3565070 3812854 3826413 3861386 Inhalation device Respiratory biofeedback and performance evaluation system 4090642 InventorsAssigneeApplicationNo. 534786 filed on 09/27/1995US Classes:128/200.22, Gas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.)128/200.14, LIQUID MEDICAMENT ATOMIZER OR SPRAYER128/204.23Means for sensing condition of user's bodyExaminersPrimary: Lewis, Aaron J.Attorney, Agent or FirmForeign Patent References
International ClassA61M 011/00AbstractDevices, packaging and methodology for creating aerosols are provided which allow for efficient and repeatable delivery of drugs to the lungs of a patient. Devices are hand-held, self-contained units which are automatically actuated at the same release point in a patient's inspiratory flow cycle. The release point is calculated by a microprocessor which receives data from a sensor making it possible to determine inspiratory flow rate and inspiratory volume. The device is loaded with a cassette comprised of an outer housing which holds a package of individual collapsible containers of pharmaceutically active drug. Actuation of the device forces drug through a porous membrane of the container which membrane has pores having a diameter in the range of about 0.25 to 6.0 microns. The porous membrane is positioned in alignment with a surface of a channel through which a patient inhales air. The flow profile of air moving through the channel is such that the flow at the surface of the channel, and thus the surface of the porous membrane is slow. The membrane is designed in a flexible manner so that when drug formulation is forced against and through the membrane the membrane protrudes outward beyond the flow boundary layer of the channel into faster moving air.Other References
Field of SearchLIQUID MEDICAMENT ATOMIZER OR SPRAYERGas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.) Means for supplying anesthetic under patient's control Means for sensing condition of user's body With wall-collapsing means By electric transducer (e.g., piezoelectric crystal) POROUS OR EXTERNAL WICK DISCHARGE MEANS | |
