Stabilized medicinal aerosol solution formulations containing ipratropium bromide
Patent 5955058 Issued on September 21, 1999. Estimated Expiration Date: 
April 14, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 14, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 5118494 Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content Medicinal aerosol formulations Medicinal aerosol formulations Medicinal aerosol formulations Patent #: 5605674 AbstractStabilized medicinal aerosol solution formulations comprising medicaments that degrade or decompose by interaction with solvents or water, an HFC propellant, a cosolvent and an acid are described. Further, specific medicinal aerosol solution formulations comprising ipratropium bromide or fenoterol, ethyl alcohol, 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoropropane, and either an inorganic acid or an organic acid are described. The acids are present in amounts sufficient to reduce the degradation of the medicaments to acceptable levels. | |
