Peptidyl prodrugs and methods of making and using the same
July 31, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesArabinofuranosyl N4 -aminoacyl cytosine containing compounds N4 -acylarabinonucleosides N4 Acyl-1-arabinofuranosylcytosine-5'-esters Diacylnucleosides and process for preparing the same Organic compounds and compositions of ara-cytidine N4 -Alkoxycarbonylarabinofuranosylcytosine Soluble and biodegradable polyamino acid activated for bonding of biologically active compound Patent #: 4745161 InventorsAssigneeApplicationNo. 690013 filed on 07/31/1996US Classes:514/2, Peptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI424/185.1, Amino acid sequence disclosed in whole or in part; or conjugate, complex, or fusion protein or fusion polypeptide including the same424/193.1, Conjugate or complex424/457, Sustained or differential release514/15, 9 to 11 peptide repeating units in known peptide chain514/18, 3 or 4 peptide repeating units in known peptide chain514/19, 2 peptide repeating units in known peptide chain536/23.1DNA or RNA fragments or modified forms thereof (e.g., genes, etc.)ExaminersPrimary: Celsa, BennettAttorney, Agent or FirmInternational ClassesA61K 038/03A61K 039/385 C07K 005/00 AbstractPeptidyl prodrugs of therapeutic agents having an activating function are sclosed. These therapeutic agents having activating functions include those having an amino, thiol, or hydroxyl function. Methods of making and using these prodrugs are also disclosed.Other References
Field of Search9 to 11 peptide repeating units in known peptide chainPeptide containing (e.g., protein, peptones, fibrinogen, etc.) DOAI 3 or 4 peptide repeating units in known peptide chain 2 peptide repeating units in known peptide chain Amino acid sequence disclosed in whole or in part; or conjugate, complex, or fusion protein or fusion polypeptide including the same Conjugate or complex Sustained or differential release DNA or RNA fragments or modified forms thereof (e.g., genes, etc.) |
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