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US Patent 5948437 - Pharmaceutical compositions using thiazepine

US Patent Issued on September 7, 1999
Estimated Patent Expiration Date: Icon_subject May 28, 2017Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

The invention relates to sustained release formulations comprising 11-›4-›2-(2-hydroxyethoxy)ethyl!-1-piperazinyl!dibenzo›b,f! ›1,4!thiazepine or a pharmaceutically acceptable salt thereof, to methods of treating psychotic states and hyperactivity utilizing the sustained release formulations and to a process for preparing the sustained release formulations.

Inventors

Assignee

Application

No. 864306 filed on 05/28/1997

US Classes:

424/464, Tablets, lozenges, or pills424/458, Containing discrete coated particles pellets, granules, or beads424/470, Where particles are granulated514/211.13Nitrogen bonded directly to ring carbon of the seven-membered hetero ring

Field of Search

424/464, Tablets, lozenges, or pills424/401, Cosmetic, antiperspirant, dentifrice540/551Nitrogen bonded directly to ring carbon of the hetero ring

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

US Patent References

3065143, 3590117, 3870790, 4226849, Sustained release therapeutic compositions
Issued on: 10/07/1980
Inventor: Schor
4259314, Method and composition for the preparation of controlled long-acting pharmaceuticals
Issued on: 03/31/1981
Inventor: Lowey
4309406, Sustained release pharmaceutical compositions
Issued on: 01/05/1982
Inventor: Guley ,   et al.
4357469, Carrier base material for prolonged release therapeutic compositions
Issued on: 11/02/1982
Inventor: Schor
4369172, Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
Issued on: 01/18/1983
Inventor: Schor ,   et al.
4389393, Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
Issued on: 06/21/1983
Inventor: Schor ,   et al.
4540566, Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose
Issued on: 09/10/1985
Inventor: Davis ,   et al.
4680323, Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
Issued on: 07/14/1987
Inventor: Lowey
4734285, Sustained release compositions
Issued on: 03/29/1988
Inventor: Alderman
4795327, Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants
Issued on: 01/03/1989
Inventor: Gaylord ,   et al.
4849229, Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants
Issued on: 07/18/1989
Inventor: Gaylord ,   et al.
4871548, Controlled release dosage form comprising different cellulose ethers
Issued on: 10/03/1989
Inventor: Edgren ,   et al.
4879288, Novel dibenzothiazepine antipsychotic
Issued on: 11/07/1989
Inventor: Warawa, et al.
4919938, Sustained release pharmaceutical compositions in oral dosage form
Issued on: 04/24/1990
Inventor: Lovegrove, et al.
5126145, Controlled release tablet containing water soluble medicament
Issued on: 06/30/1992
Inventor: Evenstad, et al.
5393765, Pharmaceutical compositions with constant erosion volume for zero order controlled release
Issued on: 02/28/1995
Inventor: Infeld, et al.
5419918Method for the manufacture of a controlled release solid unit dosage form
Issued on: 05/30/1995
Inventor: Lundberg

Foreign Patent References

  • 8663947 AU. 04/20/1987
  • 111144 EP. 06/20/1984
  • 157695 EP. 10/20/1985
  • 236002 EP. 09/20/1987
  • 253541 EP. 01/20/1988
  • 284849 A1 EP. 10/20/1988
  • 325086 EP. 07/20/1989
  • 284849 B1 EP. 08/20/1993
  • 2604902 FR. 04/20/1988
  • 3733540 DE. 04/20/1988
  • 52-145514 JP. 12/20/1977
  • 60-185728 JP. 09/20/1985
  • 62-149632 JP. 07/20/1987
  • 63-5982 JP. 01/20/1988
  • 63-101334 JP. 05/20/1988
  • 4-82826 JP. 03/20/1992
  • 6-172161 JP. 06/20/1994
  • 78/5528 ZA. 11/20/1979
  • 1430684 GB. 03/20/1976
  • 1583801 GB. 02/20/1981
  • 2195893 GB. 04/20/1988
  • 2219206 GB. 12/20/1989
  • WO 85/04100 WO. 09/20/1985
  • WO 87/00044 WO. 01/20/1987
  • WO 92/04013 WO. 03/20/1992
  • WO 92/10169 WO. 06/20/1992

International Class

A61K 009/20

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