Pharmaceutical compositions using thiazepine

Patent 5948437 Issued on September 7, 1999. Estimated Expiration Date:

May 28, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3065143

3590117

3870790

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Issued on: 10/07/1980
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Inventors

Assignee

Zeneca Limited

Application

No. 864306 filed on 05/28/1997

US Classes:

424/464, Tablets, lozenges, or pills424/458, Containing discrete coated particles pellets, granules, or beads424/470, Where particles are granulated514/211.13Nitrogen bonded directly to ring carbon of the seven-membered hetero ring

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Foreign Patent References

8663947 AU. 04/12/1987
111144 EP. 06/12/1984
157695 EP. 10/12/1985
236002 EP. 09/12/1987
253541 EP. 01/12/1988
284849 A1 EP. 10/12/1988
325086 EP. 07/12/1989
284849 B1 EP. 08/12/1993
2604902 FR. 04/12/1988
3733540 DE. 04/12/1988
52-145514 JP. 12/12/1977
60-185728 JP. 09/12/1985
62-149632 JP. 07/12/1987
63-5982 JP. 01/12/1988
63-101334 JP. 05/12/1988
4-82826 JP. 03/12/1992
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78/5528 ZA. 11/12/1979
1430684 GB. 03/12/1976
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WO 85/04100 WO. 09/12/1985
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WO 92/04013 WO. 03/12/1992
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International Class

A61K 009/20

Abstract

The invention relates to sustained release formulations comprising 11-4-2-(2-hydroxyethoxy)ethyl!-1-piperazinyl!dibenzob,f! 1,4!thiazepine or a pharmaceutically acceptable salt thereof, to methods of treating psychotic states and hyperactivity utilizing the sustained release formulations and to a process for preparing the sustained release formulations.