U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Dosage forms of risedronate

Patent 5935602 Issued on August 10, 1999. Estimated Expiration Date: Icon_subject March 12, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Direct compression cyclophosphamide tablet
Patent #: 5047246
Issued on: 09/10/1991
Inventor: Gallian, et al.

Solid pharmaceutical preparations of active form of vitamin D3 of improved stability
Patent #: 5158944
Issued on: 10/27/1992
Inventor: Makino, et al.

Dry mix formulation for bisphosphonic acids with lactose
Patent #: 5358941
Issued on: 10/25/1994
Inventor: Bechard, et al.

Bisphosphonates prevent bone loss associated with immunosuppressive therapy
Patent #: 5616571
Issued on: 04/01/1997
Inventor: Daifotis, et al.

Dosage forms of risedronate
Patent #: 5622721
Issued on: 04/22/1997
Inventor: Dansereau, et al.

Dry mix formulation for bisphosphonic acids
Patent #: 5681590
Issued on: 10/28/1997
Inventor: Bechard, et al.

Polymorphic forms of a growth hormone secretagogue Patent #: 5767124
Issued on: 06/16/1998
Inventor: Draper, et al.

Inventors

Assignee

Application

No. 820430 filed on 03/12/1997

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/463, Coated capsules424/482, Containing solid synthetic polymers424/486, Synthetic polymer424/490Coated (e.g., microcapsules)

Examiners

Primary: Levy, Neil S.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

Foreign Patent References

  • 1036368 GB. 07/13/1966

International Class

A61K 009/14

Abstract

The present invention is directed to a novel enteric-coated oral dosage form of a risedronate active ingredient comprised of a safe and effective amount of a pharmaceutical compostion which is comprised of a risedronate active ingredient and pharmaceutically-acceptable excipients. Said dosage forms prohibit the exposure of the risedronate active ingredient to the epichelial and mucosal tissues of the buccal cavity, pharynx, esophagus, and stomach and thereby protects said tissues from erosion, ulceration or other like irritation. Accordingly, the said dosage forms effect the delivery to the lower intestinal tract of said human or other mammal of a safe and effective amount of the risedronate active ingredient, and substantially alleviate the esophagitis or esophageal irritation which sometimes accompanies the oral administration of risedronate active ingredients.

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