System and method for simulating operation of biochemical systems
Patent 5914891 Issued on June 22, 1999. Estimated Expiration Date: 
June 11, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 11, 2017. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesStochastic method for finding molecular conformations Process for the estimation of physical and chemical properties of a proposed polymeric or copolymeric substance or material Method and apparatus for designing molecules with desired properties by evolving successive populations Spatially resolved stochastic simulation system Software architecture for stochastic simulation of non-homogeneous systems Patent #: 5826065 InventorsAssigneeApplicationNo. 860585 filed on 06/11/1997US Classes:703/11Biological or biochemicalExaminersPrimary: Teska, Kevin J.Assistant: Phan, Tho Attorney, Agent or FirmForeign Patent References
International ClassG06F 017/18AbstractA system and method for simulating the operation of biochemical networks includes a computer having a computer memory used to store a set of objects, each object representing a biochemical mechanism in the biochemical network to be simulated. Most objects have one or more associated signals, representing quantities or concentrations of associated proteins, positions of associated molecules, or other information concerning the state of a biochemical network. Each object has an associated set of methods. These methods include methods for determining reaction probabilities for biochemical reactions associated with the objects, and reaction simulation methods for simulating performance of those biochemical reactions. For a specified simulation time period, the operation of the biochemical network is simulated by executing at least a subset of the probability determination methods to determine reaction probabilities for at a subset of the biochemical reactions associated with the objects, selecting ones of the reaction simulation methods to execute in accordance with the determined reaction probabilities, and executing the selected ones of said reaction simulation methods. Execution of the selected reaction simulation methods causes associated ones of the signals to be updated. Output data representing values of selected ones of the signals is accumulated and presented.Other References
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