Mesenchymal stem cells for cartilage repair
May 25, 2016. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesEncapsulation of biological material Partially purified osteogenic factor and process for preparing same from demineralized bone Polypeptide cartilage-inducing factors found in bone Technique for healing lesions in cartilage Osteogenic proteins and polypeptides Neomorphogenesis of cartilage in vivo from cell culture Method and apparatus for diodegradable, osteogenic, bone graft substitute device Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells Method for treating connective tissue disorders Muscle morphogenic protein and use thereof Patent #: 5328695 InventorsAssigneeApplicationNo. 403640 filed on 03/14/1995US Classes:435/325, ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE424/423, Surgical implant or material424/426, Errodable, resorbable, or dissolving435/349, Avian cell, per se435/380Releasing bound or adhered cell using proteaseExaminersPrimary: Criares, Theodore J.Attorney, Agent or FirmForeign Patent References
International ClassesC12N 005/00C12N 005/02 A61F 002/00 AbstractIt has been discovered that mesenchymal stem cells (MSCs) in a polymeric carrier implanted into a cartilage and/or bone defect will differentiate to form cartilage and/or bone, as appropriate. Suitable polymeric carriers include porous meshes or sponges formed of synthetic or natural polymers, as well as polymer solutions. A presently preferred material is a polyglycolic acid mesh.Other References
Field of SearchErrodable, resorbable, or dissolvingSurgical implant or material ANIMAL CELL, PER SE (E.G., CELL LINES, ETC.); COMPOSITION THEREOF; PROCESS OF PROPAGATING, MAINTAINING OR PRESERVING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF ISOLATING OR SEPARATING AN ANIMAL CELL OR COMPOSITION THEREOF; PROCESS OF PREPARING A COMPOSITION CONTAINING AN ANIMAL CELL; CULTURE MEDIA THEREFORE Avian cell, per se Releasing bound or adhered cell using protease |
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