Patent ReferencesSustained release intranasal formulation and method of use thereof Fruity flavored nasal decongestant composition 5116847 InventorsAssigneeApplicationNo. 964038 filed on 11/04/1997US Classes:424/78.04, Ophthalmic preparation424/78.08, SOLID SYNTHETIC ORGANIC POLYMER AS DESIGNATED ORGANIC ACTIVE INGREDIENT (DOAI)424/434, Mucosal (e.g., nasal, etc.)424/601, Phosphorus or phosphorus compound514/772.5, Heterocyclic monomer514/853, DECONGESTANT514/912, OPHTHALMIC514/937DISPERSION OR EMULSIONExaminersPrimary: Bawa, RajAttorney, Agent or FirmForeign Patent References
International ClassA61K 009/08AbstractAqueous nasal spray compositions containing:0.001-2% by weight/volume of a medicament selected from the group consisting of chlorpheniramine maleate, oxymetazoline hydrochloride and mixtures thereof;0.50 to 15.00% by weight/volume of a water soluble polymer selected from the group consisting of polyvinylpyrrolidone having an average molecular weight of about 10,000 to 360,000 and mixtures thereof;2.5 to 10.00% by weight/volume of polyethylene glycol;1.00 to 10.00% by weight/volume of a moisturizing agent other than polyethylene glycol;0.01 to 0.05% by weight/volume of disodium edetate;0.001 to 0.3% by weight/volume of an antimicrobial preservative;0.20 to 5.00% by weight/volume of an aromatic alcohol;a sufficient amount of a pharmaceutically acceptable buffer to maintain the pH of the composition within the range of about 4.0 to 8.0; andQS water.Other References
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